The body weight, tumor growth, blood glucose and blood ketone (尾HB) values, survival time, median survival time and treatment safety of tumor-bearing mice were observed. Immunohistochemistry, multiple immunofluorescence and flow cytometry were used to detect the expression of tumor-associated micro...
Organism TypeMouseATCC# CLR1642: Cell line established from the lung of a C57BL mouse bearing a tumor resulting from an implantation of primary Lewis lung carcinoma. The cells are resistant to 1,3-bis-(2-chloroethyl)-1-nitrosourea, but are sensitive to methotrexate. The cells are reported to...
Mediators of pain and inflammation are known to be secreted from tumor cells as well as infiltrating immune cells, activating and sensitizing primary afferent nociceptors (nociceptive pain) and damaging the nervous system (neuropathic pain). However, there has been difficulty in modeling cancer-induced...
The University of Michigan team looked at tissue samples from ovarian cancer patients and separated the cells by type to study the tumor microenvironment in vitro and in mice. More importantly, the scientists linked their findings back to actual patient outcomes. The results of this study were pub...
is a cell line established from the lung of aC57BL mouse bearing a tumorresulting froman ...
InVivoOpticalMolecularIma乡ngofMiceBearing LLC-GFPTumor Abstract ObjectiveTodevelopnudemicemodelofLewislungcarcinoma(LLC) expressinggreenfluorescentprotein(GFP)stablyandhighandimage progression,furthermetastasis,angiogenesisandtheeffectofCTXontumorsin anoninvasive,alive,real-timeandsequentwaywithsmallanimalfluorescent...
Administration of cyclophosphamide changes the immune profile of tumor-bearing mice. J Immunother. 2010 Jan;33(1):53-9.[5]. Dominique A Ramirez, et al. Kinetics of Cyclophosphamide Metabolism in Humans, Dogs, Cats, and Mice and Relationship to Cytotoxic Activity and Pharmacokinetics. Drug Metab...
T cell costimulus-independent and very efficacious inhibition of tumor growth in mice bearing subcutaneous or leukemic human B cell lymphoma xenografts by a CD19-/CD3- bispecific single-chain antibody construct. J Immunol. 2003 Apr 15;170(8):4397-402.[3]. Hoffman LM, et al. Blinatumomab, ...
tumor-bearing mice were used, the size of the tumors was in the 0.2-0.5 cm3range. All compounds used were dissolved in physiological (0.9%) saline (NaCl) and the agents, alone or in combinations, were applied subcutaneously or intaperitoneally in 50-μl volume. The volume of tumor was ...
Yapp, et al., “Cisplatin delivery by biodegradable polymer implant is superior to systemic delivery by osmotic pump or i.p. injection in tumor-bearing mice,” Anti-Cancer Drugs 9: 791-796 (1998). Yapp, et al., “The potentiation of the effect of radiation treatment by intratumoral deliv...