(BMI, BM), related biochemical response measures of 1iver function (ALT, AST, ALP, GGT, TB, TP, ALB, A/G, GLB, DB), related biochemical response measures of blood sugar (FBG, FNIs, HOMA-IR, Hb1A, MRS), related biochemical response measures of blood lipids (TG, TC,HDL-C, LDL-...
Given the high prevalence of liver disease in general population adolescents, this study was designed to determine whether or not there is association between exposure to PFAAs and biomarkers of liver function in adolescent participants of the 2013-2016 National Health and Nutrition Examination Survey,...
whereas all 20 GGT variants had concordant direction of effects with cirrhosis. We found that a PRS using these 21 variants identified via endophenotype-driven analysis associated significantly with cirrhosis in the UK Biobank (UKB; odds ratio (OR): 1.15...
The high number of ACE2 receptors on the surface of the cholangiocytes in the liver18,19 bile duct cells20 presumably facilitate entry of SARS-COV-2 to the cells where they replicate leading to dysregulation of the liver function21,22. There is also evidence to suggest that most of the...
After vital microscopy plasma samples were drawn for determination of liver function by measuring aspartate transaminase (AST), alanine transaminase (ALT), alkaline phosphatase (ALP), total bilirubin (TBIL), gamma glutamyltranspeptidase (GGT), albumin, glucose, INR, PTT, haemoglobin (Hb) and platelet...
ABCB11 was first described in 1995 and initially termed sister of P-gp due to the high sequence identity of ABCB1, a classic drug export pump, and ABCB11 (Childs et al. 1995). Only in 1998, its natural function as a bile salt export pump especially for glycine and taurine conjugated...
2.6. Assessment of endothelial function Endothelial function was assessed using the EndoPAT 2000 technique, which measures PAT using the reactive hyperaemia index (RHI, arbitrary units). Briefly, after 20 min of rest in a 45° angled inclined chair, at room temperature, the blood pressure cuff ...
The Function of Homoglutathione and Hydroxymethylglutathione for the Scavenging of Hydrogen Peroxied The function of homoglutathione (纬GluCys尾Ala, hGSH) and hydroxymethylglutathione (纬GluCysSer, HMGSH) for the photoreduction of H_2O_2 was investigated. ... ZOPES,Heinrich,KLAPHECK,... - 《...
bile acids function as pleiotropic signaling molecules that mediate the crosstalk between the gut and liver57,58. The intricate interaction between bile acids and the gut flora (which involves mutual dependency and inhibition) is crucial for maintaining mammalian homeostasis. Bile acids that have not ...
The liver function was also compared between different classes of DILI. Among liver injury classes of DILI, levels of ALT and AST were significantly higher in mixed and hepatocellular liver injury group than those in cholestatic liver injury group. GGT in cholestatic liver injury group was higher ...