My GGT level was very high and my gallbladder was removed. The GGT level continues to go up, presently it is 139. I have never drank anything stronger than tea and take no medicine, not even pain meds. Present ultrasound showed liver as homogeneous in echotexture without focal lesion and...
(6) life expectancy in excess of 3 months; (7) adequate organ function – (i) hepatic: serum bilirubinp1.0 Â ULN, AST and/or ALTp2.0 Â ULN, ALP and GGTp2.5 Â ULN, if bone or liver involvement, AST or ALT, ALP and GGTp5.0 Â ULN, (ii) bone marrow: haemoglobinX100 g...
Bifidobacterium bifidum HA-132 HA-132_GB_NC2_F AAGTGTGAGCCGGTGATAGC Noncoding sequence 60 78 HA-132_GB_NC2_R CAGTACGTCGGCCGTTACAT Bifidobacterium breve HA-129 HA-129_225-F2 CGACCCTAATGACGTGGAGG Hypothetical protein 60 195 HA-129_225-R2 CATTTCAGCCAGTACGTGCG Bifidobacterium longum HA-135 ...
WC (92 ± 7 vs 89 ± 8 cm in AF vs control group respectively, p = 0.000) and GGT (59 ± 66 vs 46 ± 51, in AF vs control group respectively, p = 0.000) were higher in the AF group compared to the control group. Table 1 Baseline characteristics ...
Complete primer sequences were as follows: forward: 5′-TCGTCGGCAG:CGTCAGATGTGTATAAGAGACAGGTGCCAGCMGCCGCGGTAA-3′; reverse: 5′-GTCTCGTGGGCTCGGAGATGTGTATAAGAGACAGGGACTACHVGGGTWTCTAAT-3′. Polymerase chain reaction (PCR) mixes contained 12.5 ng of total DNA, 0.2 μmol/L of each ...
UT-Southwestern) were bred in order to produce APN KO and WT littermate controls. Mice were genotyped utilizing the following primers: ApnWTf: 5′-TTGGACCCCTGAACTTGCTTCACACC-3′, ApnWTr: 5′-TCCTGAGTTCAATTCCCAGCACCCAC-3′, ApnKOr2: 5′-GGATGCGGTGGGCTCTATGGCTTC-3′ with the following...
Here, we demonstrated that high dietary fructose drives MASLD development and promotes MASLD progression in mice, and identified Usp2 as a fructose-responsive gene in the liver. Elevated USP2 levels were detected in the hepatocytes of MASLD mice; a similar increase was observed following fructose ...
GTGCAGGGTCCGAGGT 3' 5' GTGCAGGGTCCGAGGTTTGGACCATTTCTCGAT 3' 5' GGAACGATACAGAGAAGATTAGCA 3' 5' GTGCAGGGTCCGAGGT 3' RT‑qPCR RT-qPCR was carried out by the Qiagene thermocycler (Rotor...
Carbohydrate response element-binding protein (ChREBP) is a transcription factor responsible for carbohydrate metabolism in the liver. However, the role of ChREBP in diabetic nephropathy has not been elucidated. Thus, we investigated the role of ChREBP in mesangial cells in diabetic nephropathy. ...
It is always accompanied with disorders of fatty acids (FA) oxidation, lipoprotein transport and abnormal fat synthesis in the liver (Yin et al., 2023). Currently, broilers are often fed high-energy diets to achieve rapid growth, but this can easily lead to the development of fatty liver (...