that regulate systemic inflammatory response as well as being the target of inflammatory responses.2'3 Given its central location in regulating metabolism and a response to exogenous stimuli, both physiological and pathological, every form of liver disease is accompanied by some degree of inflammation....
The application and translation of these discoveries into therapies promises novel approaches in the treatment of inflammation in liver disease.doi:10.1038/nrgastro.2015.94Gyongyi SzaboJan PetrasekNat Rev Gastroenterol HepatolNature Reviews Gastroenterology & Hepatology...
Shi, Y. Caught red-handed: uric acid is an agent of inflammation. J. Clin. Invest. 120, 1809–1811 (2010). Article CAS PubMed PubMed Central Google Scholar Seki, E. & Brenner, D. A. Toll-like receptors and adaptor molecules in liver disease: update. Hepatology 48, 322–335 (2008...
inflammation, lipid accumulation, nonalcoholic fatty liver disease, TREM‐1In the liver tissues of obese diabetic or nondiabetic patients, triggering receptor... S Rao,J Huang,Z Shen,... - Wiley-Blackwell Online Open 被引量: 0发表: 2019年 Inhibition of TREM-1 attenuates inflammation and lipid...
Pathway of the innate immune system that detects the presence of cytosolic DNA (usually indicating a viral infection or tumorigenesis) and responds by triggering the expression of inflammatory genes, such as those encoding interferon-β, which drives antiviral responses. Fatty liver disease A form of...
your liver. The extra fat can inflame your liver.MΑЅLD can progress to metabolic dysfunction-associated ѕtеаtοheрatitis (МAЅΗ).It means you have inflammation and cell damage in your liver, as well as fat. It can scar your liver and lead to other disorders, like ...
The first paper of this issue analyzed the change of etiology of liver cirrhosis patients in a hospital from 2002 to 2013 in China. They showed that the top four etiologies of cirrhosis were HBV, HCV, ALD, and autoimmune liver disease. The prevalence of HBV cirrhosis has decreased in the ...
Liver failure is a prototype of complex disease that has defied therapeut... R Zamora,Y Vodovotz - Complex Systems and Computational Biology Approaches to Acute Inflammation 被引量: 0发表: 2021年 Interleukin 22 in Liver Injury, Inflammation and Cancer Interleukin 22(IL-22), a member of the...
Inflammation has been considered as one of the hallmarks of cancer, and chronic hepatitis is a major cause of liver cancer. This review will focus on the p
acute (sudden) hepatitis (inflammation), chronic (long duration) hepatitis, fatty liver disease, cirrhosis (scarring), and cancer. Cancers that affect the liver are most commonly metastatic cancers that have spread via the bloodstream to the liver from other sites in the body. However, primary ...