The main sites of recurrence are the remnant liver, lymph nodes and lungs. Metastasis to the pancreas has never been reported. This case describes a 24-year-old woman who underwent a hepatic lobectomy in 2008 for an ICC. Almost 4 years after her surgery......
Liver Inflammation Relates to Decreased Canalicular Bile Transporter Expression in Pediatric Onset Intestinal Failurechildrenparenteral nutrition... Mutanen, AnnikaLohi, JoukoHeikkila, PaiviJalanko, HannuPakarinen, Mikko P. - 《Annals of Surgery》 被引量: 0发表: 2018年 Hepatocyte transport of bile acids...
Surgical replacement of a non-functional liver with a healthy liver from a living or deceased donor. ‘Orthotopic’ refers to the donor liver being placed in the same anatomical position as the host liver. Necrosis Premature and non-regulated form of cell death, which results in autolysis of ...
The liver is the main gateway from the gut, and the unidirectional sinusoidal flow from portal to central veins constitutes heterogenous zones, including the periportal vein (PV) and the pericentral vein zones1,2,3,4,5. However, functional differences in the immune system in each zone remain p...
The inflammasome is a cytosolic multi-protein innate immune rheostat, sensing a variety of endogenous and environmental stimuli, and regulating homeostasis or damage control. In the gastrointestinal tract, inflammasomes orchestrate immune tolerance to mi
About inflammation is our bodies natural protective system, which reacts to infection, injury etc. Learn what happens when it goes wild, and what to do about it.
Wound healing is often described as a drama, with the interplay of a multitude of different cell types, and is precisely directed to serve the ultimate goal: prompt healing [1]. Although many questions remain, extensive studies in the field have provided a general picture about this fundamental...
Five years after lung transplantation, only about half of the transplanted lungs are still functioning, according to the U.S. Organ Procurement and Transplantation Network, as against the five-year organ survival rates of about 70 to 80 percent for liver, heart and kidney transplants. ...
et al. A20 prevents chronic liver inflammation and cancer by protecting hepatocytes from death. Cell Death Dis. 7, e2250 (2016). Article CAS PubMed PubMed Central Google Scholar Kattah, M. G. et al. A20 and ABIN-1 synergistically preserve intestinal epithelial cell survival. J. Exp. ...
HMGB1 contributes to kidney ischemia reperfusion injury. J. Am. Soc. Nephrol. 21, 1878–1890 (2010). Article CAS PubMed PubMed Central Google Scholar Tsung, A. et al. The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia–reperfusion. J. Exp. Med. 201, 1135–1143...