Carbapenems are a beta-lactam antibiotic class with a broad spectrum of activity that are structurally related to the penicillins. Examples include: meropenem, ertapenem, and imipenem-cilastatin (Primaxin). Carbapenems are noted for their ability to inhibit extended spectrum beta-lactamase enzymes and...
Step therapy Step therapy requires a trial of one drug before advancing to other drugs. Certain drugs on the PDL are routinely covered only after a sufficient trial of an indicated first-line agent has been adequately tried and failed. While lower cost PDL alternatives may be appropriate in ...
2b). Three of the high-frequency pharmacological subgroups (direct acting antivirals, other beta lactam antibacterials, and antidepressants) had a statistically different ratio of DILI-positive to DILI-negative drugs in DILIst compared with DILIrank (Fig. 2b; Table 1, Column 5) driven by the ...
First-generation cephalosporins inhibit bacterial cell wall synthesis and have the same mode of action as other beta-lactam antibiotics (such as penicillins). They disrupt the synthesis of the peptidoglycan layer forming the bacterial cell wall. The peptidoglycan layer is important for cell wall struc...
Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 United States Patent 8629138 Abstract: Disclosed is a compound represented by Formula (Im1): or a pharmaceutically acceptable salt, monohydrate, enantiomer or diastereomer thereof. Also disclosed are pharmaceutical compositions comprising the ...
It is believed that the glass transition temperature Tg of PVP increases as the molecular weight of PVP increases. Surface activity of PVP Observe from the structural unit of PVP monomer NVP, it contains a lactam base with higher polarity that has strong ability of affinity polar group, ...
DB33/T 473—2004β-内酰胺类、磺胺类和氨基糖苷类链霉素型药物残留量的测定 放射免疫快速检测法Determination of beta-lactam,sulfa drugs and aminoglycoside-St residues--Radioimmunoassay 浙江省地方标准... 授权方式: 免费运行平台: Win9X/Win2000/WinXP955...