BETA-LACTAM ANTIBIOTICNEW MATERIAL:A cephalosporin derivative (salt) shown by the formulaI[R1 is COOH, CONH2, CH=NOCH3 (E form or Z form), CH2OH, or CHO]. EXAMPLE:7(R)-7-[2-(2-Carbamoylthiazole-4-yl)acetamido]cephalosporanic acid. USE:An antibacterial agent against Gram-positive ...
beta-lactam antibiotic (redirected fromBeta-lactam antibiotics) Medical Encyclopedia Related to Beta-lactam antibiotics:beta-lactamase,Aminoglycosides n. Any of a class of broad-spectrum antibiotics, such as the penicillins and the cephalosporins, that contain a beta-lactam ring. ...
Meropenem trihydrate(美罗培南三水合物)是一种碳青霉烯类抗生素。在体外对革兰氏阳性和革兰氏阴性细菌的临床分离株有活性,包括肺炎链球菌、流感嗜血杆菌、淋球菌、大肠杆菌、铜绿假单胞菌、艰难梭菌、 和对甲氧西林敏感和耐药的金黄色葡萄球菌(MICs = ≤0.008-8 μg/ml)。图1.Meropenem trihydrate化学结构Meropenem ...
Cephalosporins are β-lactam antibiotics, which are grouped into four generations according to their antibiotic spectrum of activity (Simon and Stille, 1997). The first generation has mainly gram-positive activity. The second and third generation has more gram-negative activity with decreased activity ...
BRL 17421 is a new semisynthetic beta-lactam antibiotic with an unusual spectrum of antibacterial activity. The compound exhibits exceptional stability to a wide range of bacterial beta-lactamases and is active against the majority of Enterobacteriaceae, including strains highly resistant to many of the...
Staphylococcusspp.[49,50]. However, occurrence of bacterial resistance has restricted the use of first generation forever. Bacteria mainly developed a high level of resistance by producing β-lactamase enzymes that basically destroy the β-lactamantibioticthrough the opening of four-memberedlactamring[...
Names: Amoxicillin, beta-lactam antibioticCAS号: 26787-78-0 MDL Number: MFCD00056860 MF(分子式): C16H19N3O5S MW(分子量): 365.40EINECS:248-003-8 Reaxys Number: Pubchem ID:33613 Brand:BIOFOUNT 阿莫西林(Amoxicillin,26787-78-0)是具有杀菌活性的广谱半合成氨基青霉素抗生素的无水形式。阿莫西林与位于...
Inhibition of β-lactamase of Bacillus licheniformis 749/C by compound PS-5, a new β-lactam antibiotic By use of a new computer-assisted u.v.-spectrophotometric assay method, the kinetic parameters of the reaction catalysed by Bacillus licheniformis 749/C be... Y Fukagawa,T Takei,T Ishikura...
A method for crystallizing a beta-lactam antibiotic 本发明涉及结晶β-丙酰胺的方法,其中β-内酰胺是由硝酸溶液中结晶的. The present invention relates to a crystalline β- propionamide, wherein the β- lactam i... T·范德尔德斯,R·H·奎珀斯 被引量: 0发表: 2001年 A METHOD FOR CRYSTALLIZING...
antibiotic beyond the maximum time provided in the manufacturer stability data: 1. Toxicity: does a product of degradation cause patient harm? Meropenem and piperacillin/tazobactam are not known to have any issues relating to harmful products of degradation....