Antineoplasticanthracyclines are a class of drugs used to treat various cancers, includingleukemia(acutelymphocyticleukemia and acute myeloid leukemia), lymphomas, cancers of the breast, stomach,uterus, ovary,bladder, andlungs, Hodgkin'slymphoma(cancer of the lymphatic system), and non-Hodgkin's lympho...
For example, DICT keywords were found in the WP section of the labeling for dexrazoxane hydrochloride injection within the following statement: ‘Cardiac toxicity: Totect [brand name] does not completely eliminate the risk of anthracycline-induced cardiac toxicity. For cardiomyopathy, monitor cardiac ...
15mg/45mg per vial In combination with capecitabine for the treatment of patients with metastatic or locally advanced breast cancer resistant to treatment with an anthracycline and a taxane, or whose cancer is taxane resistant and for whom further anthracycline therapy is contraindicated. 185. Halo...
AHA 2024 Common Heart Failure Drugs Ease Heart Damage During Chemo The combination of sacubitril and valsartan reduces the cardiotoxicity related to anthracycline chemotherapy drugs, according to the first randomized study of this approach. Medscape Medical News, November 19, 2024 2 AHA 2024 New...
Torgov et al., “Generation of an intensely potent anthracycline by a monoclonal antibody-beta-Qalactosidase conjugate,” Bioconjugate Chern. 16(3):717-721 (2005). van Dijk et al., “Human antibodies as next generation therapeutics,” Curr Opin Chern Biol. 5(4):368-374(2001). Vessel...
Paclitaxel Injection is indicated for the treatment of breast cancer after failure of combination chemotherapy for metastatic disease or relapse within 6 months of adjuvant chemotherapy. Prior therapy should have included an anthracycline unless clinically contraindicated. Paclitaxel Injection, in combination ...
The initial dose of Gengraf varies depending on the transplanted organ and the other immunosuppressive agents included in the immunosuppressive protocol. What Drugs, Substances, or Supplements Interact with Gengraf Oral Solution? Gengraf Oral Solution may interact with "live"vaccines, grapefruit, etopos...
Follow guidelines for handling and disposal for hazardous drugs, including the use of gloves and other protective clothing to prevent skin contact1. REFERENCES 1. “OSHA Hazardous Drugs” (refer to antineoplastic weblinks including OSHA Technical Manual). OSHA. http://www.osha.gov/SLTC/hazardousdru...
Ninety-four percent (94%) of patients received anthracycline and taxane chemotherapy. Twenty-six (26%) of patients overall had received prior platinum for breast cancer. Ninety percent (90%) of patients with hormone receptor positive breast cancer received concurrent endocrine therapy. Patients ...