Introduction:Anthracyclines (AC), a class of chemotherapeutic drugs, are used to treat various cancers, including breast cancer (BC). However, AC cause dose-dependent cardiac toxicity. Practice guidelines list pre-existing cardiomyopathy as a risk factor for cancer therapy-related cardiac dysfunction ...
Antineoplastic anthracyclines work in the following ways: As an anthracycline type ofchemotherapyfor treating several types of cancers. Slowing down or stopping the growth of certain cells, including cancer cells and cells that affect the body's natural defenses. HOW ARE ANTINEOPLASTIC ANTHRACYCLINES USED?
Cancer patients know chemotherapy can be a life-saver, but the side effects are notorious. One common complaint is that the treatment leaves them feeling foggy-headed and forgetful, unable to concentrate or focus as well as they used to. It's been nicknamed "chemo brain." Chemotherapydrugs ca...
It has been over three decades since anthracyclines took their place as the standard chemotherapy backbone for breast cancer in the curative setting. Though the efficacy of anthracycline chemotherapy is not debatable, potentially life-threatening and long-term risks accompany this class of agents, leadi...
Further study shows the sensitivity of the acetaldehyde dehydrogenase 2 mediated anthracycline type chemotherapy drugs to tumor cells, thus remaindering the application of the acetaldehyde dehydrogenase 2 as the drug target for treating tumor cells with the anthracycline type chemotherapy drugs. Deletion ...
Retracted: Efficacy of Chinese Medicine Injection for Cardiotoxic Injury of Anthracycline Chemotherapy Drugs: A Network Meta-Analysis of Randomized Controlled Trialsdoi:10.1155/2023/9795740DIABETESDRUG resistance in microorganismsand Alternative Medicine, Evidence-Based Complementary...
However, anthracycline-based chemotherapy has a number of serious side effects, limiting the lifetime dosage of those drugs [3]. One of the most severe adverse events classically associated with this class of drug is anthracycline-induced cardiotoxicity (AIC). It typically leads to the progressive...