A rhesus monkey model for familial hypercholesterolemia was established. The affected animals were heterozygous for a nonsense mutation of the LDL -receptor gene in a position 284 of exon 6 and presented with high plasma levels of total cholesterol, LDL cholesterol and apo B . Plasma concentration...
Lp(a) levels wereestimated by in vitro turbidometric immunoassay using a kit.. It was seen that mean level ofTotal Cholesterol, Triglyceride, Very Low Density Lipoprotein-Cholesterol and Low DensityLipoprotein-Cholesterol were significantly higher in children with family history ofpremature ischemic ...
In the control group, the significant positive correlation between Lp(a) and LDL-C was no longer significant after correction for the estimated contribution of Lp(a) cholesterol to LDL-C. These cross-sectional data suggest that a lifestyle of moderate to intense exercise training does not exert...
We investigated lipids and lipoproteins and their inter-relationships considering the disease activity. In this study, we measured total cholesterol, triglycerides, HDL-cholesterol, LDL-cholesterol, apolipoprotein A-1, apolipoprotein B, and cholesterol-rich lipoprotein (a) [Lp(a)], which is accepted ...
Fasting plasma glucose (FPG), 2-h post-load plasma glucose (2-h PG), triglycerides (TG), total cholesterol (TC), high-density lipoprotein-cholesterol (HDL-C), and LDL-C were measured using an autoanalyser (ADVIA-1650 Chemistry System, Bayer Corporation, Germany). Serum Lp(a) levels ...
Associations between lipoprotein(a) levels and cardiovascular outcomes in black and white subjects: the Atherosclerosis Risk in Communities (ARIC) Study. Circulation. 2012;125(2):241-249. doi:10.1161/CIRCULATIONAHA.111.045120 PubMedGoogle ScholarCrossref 16. Nave AH, Lange KS, ...
Lipoprotein(a) levels and risk of future coronary heart disease: large-scale prospective data. BACKGROUND: Large-scale prospective data are needed to determine whether associations between lipoprotein(a) (Lp[a]) and coronary heart disease (CHD) risk ......
Although the association between circulating levels of lipoprotein(a) [Lp(a)] and risk of coronary artery disease (CAD) and stroke is well established, its role in risk of peripheral arterial disease (PAD) remains unclear. Here, we examine the association between Lp(a) levels and PAD in a...
lipoprotein(a) risk prediction Abbreviations and Acronyms CHD coronary heart disease CI confidence interval HDL high-density lipoprotein IDI integrated discrimination improvement KIV-2 kringle IV type 2 LDL low-density lipoprotein MI myocardial infarction NRI net reclassification index SNP single nucleotide ...
ASCVD indicates atherosclerotic cardiovascular disease; GRS, genetic risk score; Lp(a), lipoprotein(a); LDL-C, low-density lipoprotein cholesterol. To convert LDL-C to millimoles per liter, multiply by 0.0259; Lp(a) to milligrams per deciliter, divide by 2.4. ...