A rhesus monkey model for familial hypercholesterolemia was established. The affected animals were heterozygous for a nonsense mutation of the LDL -receptor gene in a position 284 of exon 6 and presented with high plasma levels of total cholesterol, LDL cholesterol and apo B . Plasma concentration...
ASCVD indicates atherosclerotic cardiovascular disease; GRS, genetic risk score; Lp(a), lipoprotein(a); LDL-C, low-density lipoprotein cholesterol. To convert LDL-C to millimoles per liter, multiply by 0.0259; Lp(a) to milligrams per deciliter, divide by 2.4. ...
Troglitazone is a new oral antidiabetic agent able to reduce lipid peroxidation. In this study we evaluated its effect on the susceptibility of LDL and HDL... L Cominacini,U Garbin,AM Pastorino,... - 《Diabetologia》 被引量: 195发表: 1997年 LIPOPROTEIN ABNORMALITIES IN INSULIN-DEPENDENT DI...
oxidized LDL(oxLDL)and Liporotein(a) LP(a) in plasma in 125 patients with cerebral in- faretion cerebral hemorrhage and coronary atherosclerotic heart disease as well as 28 normal subjects were evaluated.The results showed that the amount Of oxLDL and LP(a) in three groups was significantly...
Lipoprotein(a) [Lp(a)], a low-density lipoprotein (LDL)-like particle with a large glycoprotein, apolipoprotein(a) [Apo(a)], is covalently bound to apolipoprotein B 100 by a disulfide bridge[1]. Apo(a) genotype determines both the synthetic rate and size of the Apo(a) moiety of Lp(...
TRLP and LDLP subfraction concentrations and their average sizes were measured using the LP4 algorithm of the Vantera nuclear magnetic resonance platform. HOMA-IR was used as measure of insulin resistance. HOMA-β was used as a proxy of β-cell function. Results In subjects without T2D at ...
To enlighten therapeutic effect and mechanism of action of BAT with particular regard to patients with chronic kidney disease and hypertensiondoi:10.1016/0021-9150(94)93681-1A.A. KroonP.N.M. DemackerA.F.H. StalenhoefAtherosclerosis
Lipoprotein Particle Profiles, Standard Lipids, and Peripheral Artery Disease Incidence: Prospective Data From the Women's Health Study Background: Despite strong and consistent prospective associations of elevated low-density lipoprotein (LDL) cholesterol concentration with incident corona... Aday, Aaron ...
Conclusions: Lipoprotein (a) is a significant independent risk factor for PVD. Lp(a) levels correlated with LDL, cholesterol, fibrinogen, apolopoprotein B and disease severity, An elevated Lp(a) level may be associated with more severe forms of PVD. 展开 关键词: Lipoprotein (a) Peripheral ...