There is emerging evidence that lipids and lipid metabolism are essential for cancer growth. In hepatocellular carcinoma a decline of apoptotic lipids like ceramides is supposed to hinder death of cancer cells. Accumulation of saturated fats may protect the cells from oxidative stress. Enhanced lipogene...
Several of these functions are related to the unique physico-chemical properties shared by all lipid species, i.e., their hydrophobicity. The latter, however, is accompanied by a poor solubility in an aqueous environment and thus a severe limitation in the transport of lipids in aqueous ...
Sterols occur naturally in animal foods as cholesterol and in plant foods as phytosterols; they can also be made commercially. Triglycerides are the main form of lipid (fat) that is found in the body and in food. A triglyceride is made of a molecule of glycerol, which provides the “...
Type 2 diabetes mellitus (T2DM), one of the main types of Noncommunicable diseases (NCDs), is a systemic inflammatory disease characterized by dysfunctional pancreatic β-cells and/or peripheral insulin resistance, resulting in impaired glucose and lipid metabolism. Genetic, metabolic, multiple lifestyl...
Digestion and absorption of lipids Lipid digestion Dietary lipids:TAGs, phospholipids, andcholesterolesters Not readily absorbed byenterocytesdue to: Hydrophobic properties Large molecular size Firstbroken down bylipases;in the mouth,stomach, and intestinal lumen andpackaged intomicelles ...
Lipid ; Fatty acids & Glycerol. C Carbohydrate ; Fatty acids only. D Lipid ; Ribose. 6 concept Phospholipids Video duration: 4m 7 Problem How do phospholipids interact with water molecules? a) The polar heads avoid water; the nonpolar tails attract water (because water is polar and opposites...
Fatty acid desaturation is central to metazoan lipid metabolism. Here, using C. elegans as a model, the authors show that both endogenous and microbiota-dependent small molecule signals converge to promote lipid desaturation via the nuclear receptor NHR-49/PPARα. Bennett W. Fox , Maximilian J....
Thus, long chains of carbon-hydrogens bonds form a nonpolar molecule. The bonding differences between water and lipid molecules is important because “like attracts like.” As a polar solvent, water prefers to dissolve molecules with polar bonds, such as salt and sugar. Molecules with nonpolar ...
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Type II NKT Cells and Their Emerging Role in Health and Disease NKT cells recognize lipid Ags presented by a class I MHC-like molecule CD1d, a member of the CD1 family. Although most initial studies on NKT cells focused... MV Dhodapkar,V Kumar - 《Journal of Immunology》 被引量: 38...