in understanding lipid digestion, post-absorption metabolism, and physiological processes (e.g., cell division and differentiation, immune function and inflammation); and in metabolic oxidative stress in the animal and lipid peroxidation, necessitates a more compressive assessment of factors affecting the...
In our previous works we have shown strong evidences that grapevine resistance to the biotrophic oomycetePlasmopara viticola, the downy mildew causing agent, could be mediated on the first hours of interaction by JA and lipid associated signalling6,7,8. Indeed, we have shown that the content in...
This has lead to the hypothesis that the HDL in some individuals might be dysfunctional as an anti-atherogenic agent or perhaps even proatherogenic as a result of the HDL lipid content, particularly that of S1P. In the present study, we addressed this hypothesis by measuring levels of S1P ...
Several methods are used to restore native-like conditions. For example, amphipathic polymers (known as “amphipols”) are used to replace the detergent3. Lipid nanodiscs, surrounded by membrane scaffolding proteins, are used for both functional and structural studies4. Another commonly used method...
Lipid-based vectors have also been used in nucleic acid therapies and have been formulated in one of two ways. In one method, the nucleic acid is introduced into preformed liposomes or lipoplexes made of mixtures of cationic lipids and neutral lipids. The complexes thus formed have undefined an...
Lastly, we show that these effects may be promoted by specific bacterial strains through microbe-derived components or small molecules. Results GF Mice Are Protected from HF Diet-Induced Obesity, in Part by Decreased Dietary Lipid Digestion and Absorption To establish whether GF mice display signs ...
Lipofection has been studied as a means of altering the genetics of cells through lipid mediated gene delivery since at least 1987. Over years, refinements have been made to such lipids to adapt them to more situations. Cationic lipids like DODAC, DOTMA, DDAB, and DOTAP were used in the ...
Dopey1-Mon2 complex functions as a dual-lipid-regulated cargo-adaptor to recruit kinesin-1 to secretory and endocytic organelles or membrane carriers for centrifugally biased bidirectional transport. Dopey1-Mon2 complex therefore provides an important missing link to coordinate the budding of a ...
Dopey1-Mon2 complex functions as a dual-lipid-regulated cargo-adaptor to recruit kinesin-1 to secretory and endocytic organelles or membrane carriers for centrifugally biased bidirectional transport. Dopey1-Mon2 complex therefore provides an important missing link to coordinate the budding of a ...
The endocannabinoids (eCBs)—the lipid mediators of the ECs—are activators of the cannabinoid receptors (CB1 and CB2). Arachidonoylethanolamide (AEA) (also named anandamide) and 2-arachidonoylglycerol (2-AG) are both well-known eCBs. Meanwhile, other ethanolamide lipid mediators, namely the...