In this study, we determined the efficiency and efficacy of cationic lipid nanoparticles to deliver pre-miR-107 (NP/pre-miR-107) in HNSCC cells in vitro and in vivo . NP/pre-miR-107 increased delivery of miR-107 into HNSCC cells by greater than 80,000-fold compared to free pre-miR-...
Among these, lipid-based nanoparticles have great potential owing to their biocompatibility and low toxicity in comparison with inorganic nanoparticles and viral systems. This review discusses the hurdles of systemic siRNA delivery and highlights the recent progress made in lipid-based nanoparticles, which...
Hybrid Magnetic Lipid-Based Nanoparticles for Cancer Therapy Cancer is one of the major public health problems worldwide. Despite the advances in cancer therapy, it remains a challenge due to the low specificity of t... MT Luiz,JA Dutra,J Viegas,... - 《Pharmaceutics》 被引量: 0发表: 202...
Lipid-based nanoparticles for contrast 来自 ResearchGate 喜欢 0 阅读量: 27 摘要: In the field of MR imaging and especially in the emerging field of cellular and molecular MR imaging, flexible strategies to synthesize contrast agents that can be manipulated in terms of size and composition and ...
Lipid-based nanoparticulate delivery systems for HER2-positive breast cancer immunotherapyBreast cancerHER2ImmunotherapyLipid-based nanoparticles... N Behravan,F Zahedipour,MR Jaafari,... - 《Life Sciences》 被引量: 0发表: 2022年 Advanced biomaterials for cancer theranostic immunotherapy is given, portr...
Introduction: Liposomes and lipid-based nanoparticles (LNPs) effectively deliver cargo molecules to specific tissues, cells, and cellular compartments. Patients benefit from liposomal drug formulations by altered pharmacokinetic properties, higher efficacy, or reduced side effects. While liposomes are an esta...
Among these, lipid-based nanoparticles bear the advantage of being the least toxic for in vivo applications, and significant progress has been made in the area of DNA/RNA and drug delivery using lipid-based nanoassemblies. In this review, we will primarily focus on the recent advances and ...
Scientists and clinicians at OSU and OHSU have demonstrated proof-of-concept for a much better means of therapy: loading chemically modified CFTR messenger RNA into lipid-based nanoparticles, creating molecular medicine that could simply be inhaled at home. ...
Folate-linked lipid- based nanoparticles deliver a NFκB decoy into activated murine macrophage-like RAW264.7 cells. Biol. Pharm. Bull. 2006, 29, 1516-... Y Hattori,M Sakaguchi,Y Maitani - 《Biological & Pharmaceutical Bulletin》 被引量: 45发表: 2006年 Folate-Linked Lipid-Based Nanoparticles...
The low aqueous solubility (< 1.0 μg/mL; log P = 3.96) limits 关键词: Nanoemulsion Solid lipid nanoparticles Nanostructured lipid carriers Antitumor drug Cytotoxicity Nanomedicine DOI: 10.1007/s11051-017-4042-0 年份: 2017 收藏 引用 批量引用 报错 分享 ...