Cell membrane coating integrity affects the internalization mechanism of biomimetic nanoparticles Lizhi Liu Xuan Bai Vesa-Pekka Lehto Nature Communications(2021) Non-disruptive uptake of anionic and cationic gold nanoparticles in neutral zwitterionic membranes ...
that do not fit the general description of lipids. For example, fatty acids comprising one to four carbons in their aliphatictailsare completely miscible with water and insoluble in nonpolar solvents. The lack of a common subunit makes lipids distinct from othermacromoleculesthat also serve as macro...
By radially integrating around the [100]LBragg peak, Herman’s orientation function,\(H = \frac{3}{2} < {\mathrm{cos}}^2(\psi ) > - \frac{1}{2}\), was used to determine membrane orientation. Perfectly oriented membranes showH = 1 while randomly oriented membranes would result ...
The nuclear envelope then reassembles, enclosing the chromatin-associated NPC precursors in the nascent membrane as the NPC maturates [15]. In contrast, during nuclear expansion in G1 and G2 phases of the cell cycle, novel NPCs are embedded into the growing, but still intact, nuclear envelope...
Membrane Structure and Function: Relevance in the Cell's Physiology, Pathology and Therapy Garth L. Nicolson, Michael E. Ash, in Biochimica et Biophysica Acta (BBA) - Biomembranes, 2014 1 General introduction The use of dietary membrane lipids and oral and intravenous lipid supplements to modify...
The tilt angle of the cholesterol and the conformation of the phospholipid fatty acid tails both showed a lower level of order in leukemic cell membranes compared with normal cell membranes. The lateral radial distribution function of the lipids also showed a more disordered structure in leukemic ...
3 eicosanoids *fattyacidsabsent Functions Energysource –storagecompounds(triacylglycerols)Hydrophobicbarriers –membraneconstituents(phospholipids&glycoplipids)Functional –––––protectivecoverings(waxes)Buoyancyinaquaticorganismsregulatorypropertiese.g.coenzymeshormones(steroids,prostaglandins,vitamins)signallinge.g....
Influenza Virus Assembly and Lipid Raft Microdomains: a Role for the Cytoplasmic Tails of the Spike Glycoproteins Influenza viruses encoding hemagglutinin (HA) and neuraminidase (NA) glycoproteins with deletions in one or both cytoplasmic tails (HAt− or NAt−) hav... Jie,Zhang,Andrew,... -...
These domains target DHHC protein on different membrane and also form a binding pocket for Acyl-CoA. In contrast, the intracellular C- and N-terminal cytoplasmic tails possess great sequence diversity and mediate protein-protein interaction, thus bring the substrates closer and facilitate the acyl‐...
In aqueous systems, the polar lipids spontaneously form micelles, by which the hydrophobic hydrocarbon tails are hidden from the surrounding water. On the surface of water (water/air interphase), they form monolayers with the hydrophobic tails pointing out toward the air. The cell membrane is an...