Supervised learning denotes the learning process of an algorithm using labelled data, meaning data that contains the target value for each data instance, e.g., tear film lipid layer category. From: The Ocular Surface, 2022 About this pageSet alert ...
25,26 Previous genetic association studies have pointed to a potential role of lipids in AAA pathology,10,11,27 but this current study uses a larger panel of single-nucleotide polymorphisms (SNPs), a considerably larger sample, and more advanced methods. Mendelian randomization (MR) is an ...
Executive summary of the third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III). JAMA. 2001;285(19):2486-2497. doi:10.1001/jama.285.19.2486 ArticlePubMed...
A panel of control proteins was purified to dissect the necessary components of a cytosolically-delivered bioPROTAC system (Fig. 3E, Supplementary Fig. 2b). Specifically, a binder-only control (no E3 domain), binding-deficient controls (K27n3), and non-charged (no ApP) variants were cloned...
These results suggest that peroxisomes are required for regulation of phospholipid metabolic pathways, immune pathways, stress response pathways, and cytoskeleton remodeling during infection (Figure 1D). Indeed, these functions were either not enriched or differentially enriched when we compared the gene ...
deriving meaning from peak lists spanning dozens or hundreds of samples is no simple task. Manual interpretation of data using publically available databases such as KEGG pathways and the LipidMAPS databases may help place quantitated lipidomics results into a meaningful biological context. Similarly, ...
Results and discussion MS-DIAL 5 was designed to handle multimodal MS data, where the main focus in this study is to develop an environment for in-depth structure elucidation using EAD (Table1). We initially assessed the informational content of EAD-MS/MS by examining the spectra of 716 uniq...
3e, right panel). The formed structures had a unique morphology and apparently contained very tight protein-mediated adhesions; these junctions are likely to represent PLP-mediated membrane stacks, resembling those observed in CNS compact myelin [37]. X-ray diffraction and atomic force microscopy ...
[to convert to millimoles per liter, multiply by 0.0113] at 2 consecutive annual visits, or at 1 visit followed by treatment with a lipid-lowering medication) and were using a lipid-lowering drug or were not using a lipid-lowering drug but had lipid panel results outside of reference ...
Results Of the 28 024 participants included in the analysis, 26 476 participants (94.5%) did not develop CHD and incident CHD occurred in 1548 participants (5.5%) during the study period. Most baseline characteristics differed between CHD cases and noncases (Table 1; eTable 5 in theSuppleme...