Our results also highlighted the utility of a multimarker panel in delineating dementia from NCI patients as well as all other diagnoses. The analyses to distinguish AD or VaD from all other diagnoses is more representative of the population, as compared to distinguishing AD or VaD from NCI alon...
National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). Third report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Chole...
According to our results, decreased physical activity (including vigorous, moderate intensity or walking activities) may cause an increase in blood lipids, except HDL; body mass index, and a decrease in quality of life. Additionally increased blood lipids decrease different areas of quality of life...
=0.0027). Furthermore, another rare missense variant was recently shown to have a large impact on blood pressure in a large meta-analysis [78]. RBM47 encodes an RNA-binding protein essential for post-transcriptional modification of the apoB mRNA in particular. This modification creates a ...
cluster were positively correlated with the clinical lipid panel and blood glucose levels but negatively correlated with CRP level and neutrophils. This suggests that early changes in energy metabolism (reduction in lipid and blood glucose levels) are coupled with increased inflammation (reduction in ...
The genetic determinism of blood lipid concentrations, the main risk factor for atherosclerosis, is practically unknown in species other than human and mouse. Even in model organisms, little is known about how the genetic determinants of lipid traits are
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(falling below the detectable range using the anti-human insulin antibody). Consequently, it is inferred that the blood lipid-improving impact of CM may be attributed to components other than insulin-like peptides [84]. In that essence, the multiplex panel analysis revealed that the CM samples...
“genome-wide biomarker MR”, based on summary statistics from GWAS of blood lipids and CHD. Next, we use these data to select genes associated with blood lipids that encode druggable targets and test the effects of these drug targets on CHD using “drug target MR” in two independent ...
Expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel III) final report. Circulation. 2002;106:3143–421. Google Scholar Fenger M. Heritability and genetics of lipid metabolism. Futur Lipidol. 2007;2:433–44. Article CAS Google Scholar...