This review also emphasize on methods to minimize the toxic and overdosing effects of drugs using sophisticated production techniques like homogenization and solvent evaporation. It pave the arena for the acceptance of solid lipid nanoparticles as novel or targeted drug delivery system through using ...
Solid lipid nanoparticlesdrug deliverydrug targetinggene deliverynanosctructured lipid carrierspatentsIntroduction: Solid lipid nanoparticles (SLNs) are solid core lipid nanocarriers, which can hold both hydrophilic and hydrophobic drugs. They can be made up of biocompatible ingredients and therefore are ...
Lipid nanoparticles have successfully entered the clinic for the delivery of mRNA; in particular, lipid nanoparticle–mRNA vaccines are now in clinical use against coronavirus disease 2019 (COVID-19), which marks a milestone for mRNA therapeutics. In this Review, we discuss the design of lipid ...
Harnessing mRNA–lipid nanoparticles (LNPs) to treat patients with cancer has been an ongoing research area that started before these versatile nanoparticles were successfully used as COVID-19 vaccines. Currently, efforts are underway to harness this platform for oncology therapeutics, mainly focusing on...
Intl J of Nanoparticles. 2010;3(1):32-52.Thiruganesh, R. ; Devi, S. K. U.: Solid lipid nanoparticle and nanoparticle lipid carrier for controlled drug delivery - a review of state of art and recent advances. In: ... R Thiruganesh,SKU Devi - 《International Journal of Nanoparticles...
Shendge. Solid Lipid Nanoparticles: A Review. Nanoscience and Nanotechnology Research. 2017; 4(2):67-72. doi: 10.12691/nnr-4-2-5 AbstractSolid lipid nanoparticles are at the forefront of the rapidly developing field of nanotechnology with several potential applications in drug delivery, clinical ...
Among these, lipid-based nanoparticles have great potential owing to their biocompatibility and low toxicity in comparison with inorganic nanoparticles and viral systems. This review discusses the hurdles of systemic siRNA delivery and highlights the recent progress made in lipid-based nanoparticles, which...
These core/shell type nanoparticles, frequently referred to as lipid-polymer hybrid nanoparticles (LPNs), possess several characteristics that make them highly suitable for drug delivery. This review introduces the formulation methods used to synthesize LPNs and discusses the strategies used to treat ...
Lipid nanoparticles are essential to mRNA vaccines. The groundwork for lipid-based drug delivery systems was laid more than 40 years ago in the lab of Pieter Cullis, Professor at the University of British Columbia. Nature Reviews Materials talks to Pieter Cullis about the history and future of ...
Nature Reviews Bioengineeringthanks Natalie Trevaskis and the other, anonymous, reviewers for their contribution to the peer review of this work. About this article Cite this article Couvreur, P., Lepetre-Mouelhi, S., Garbayo, E.et al.Self-assembled lipid–prodrug nanoparticles.Nat Rev Bioeng1...