GSE7890和GSE44270的瘢痕疙瘩脂代谢相关基因还分别显著富集在血管内皮生长因子信号通路、鞘磷脂代谢及信号通路和初级胆汁酸生物合成等。 Figure 2 Gene ontological biological process and KEGG enrichment analysis of differential lipid metabolism-related genes in keloid in GSE7890 and GSE44270. 图2 GSE7890、GSE4...
Through Kyoto Encyclopedia of Genes and Genomes (KEGG) and Gene Ontology (GO) functional enrichment analyses of transcriptome sequencing data, we observed that MIER2 was significantly involved in protein deacetylation, transcriptional regulation by TP53, and regulation of lipid metabolic processes (Fig. ...
We first downloaded the colorectal cancer dataset (Supplementary Data1) from the TCGA database and analyzed it by GO analysis and KEGG analysis using the Metascape database. The fatty acid metabolic pathway genes enriched in the Reactome gene set in the GO form were analyzed (Supplementary Fig.1...
Fig. 1: Metabolic landscape of patients with hyperlipidemia and hypertension. a Overview of the study design. b, c Counts and classes of metabolites detected by metabolomics in human serum. d The heatmap shows the different metabolites between the different groups. e KEGG analysis of differentially...
GO/KEGG functional enrichment analysis was subsequently performed, and the results illustrated that these 16 LRGs were involved in the triglyceride metabolic process, fatty acid binding, PPAR signalling pathway, and mTOR signalling pathway. FABP7, which regulates lipid metabolism, has been found to ...
Lipid Identification & Functional Annotation (KEGG pathway, metabolic network analysis) Comprehensive Data Interpretation Our expert team ensures optimized protocols, stringent quality control, and in-depth statistical analysis to deliver highly accurate lipidomics insights. Untargeted Lipidomics Data Analysis...
Comparison of gene sets with respect to functional categories revealed a higher gene number assigned to the category “carbohydrate metabolic process” and in “fatty acid biosynthetic process” in M. neglectum when compared to Chlamydomonas reinhardtii and Nannochloropsis gaditana, indicating a higher ...
Lipids play an important role in the growth and metabolism of the human body, including energy storage, metabolic regulation, fat-soluble vitamins absorption, and bile salt production (Schulz et al., 2020). Apart from providing nutrition, lipids also contributed to the aroma, palatabililty and ...
This observation suggests that KGS-NE may attenuate cellular susceptibility to viruses by diminishing ACE2 gene expression, thereby decelerating the process of virus invasion into host cells. Furthermore, as shown in Figure S4, KEGG pathway analysis identified significant expression of ABC transporter ...
3C). KEGG analysis indicated that DEMLRGs were related to “metabolic pathways”, “inositol phosphate metabolism”, and “glycerophospholipid metabolism” (Fig. 3D). Reactome analysis suggested that DELMRGs were significantly enriched in “metabolism of lipids”, “metabolism”, and “metabolism of ...