elements NA to NE, and individual orthologous genes are rarely found on different elements. However, the NN and NX elements that, together, constitute theC. elegansX (see also below) are exceptions. We now study the sex chromosomes of species from all major nematode clades, and assign their ...
Several forms of infantile epilepsy also show similar cellular interference, but fortunately no other examples are known. Yet, there are females who express an X-linked pathogenic variant, even though most carriers of pathogenic variants in similar genes do not. For example, females with Fabry ...
Specific versions of genes, or gene variants, have been tied to these disorders, but not much is known about the influence of HERVs. Related: Common cold virus may predate modern humans, ancient DNA hints "We were fascinated by the concept that [HERVs] existed in the human ge...
Genetic linkage is one of the crucial abilities of the genes present nearly close to each other on a particular chromosome and are generally inherited together. It takes place during the meiotic division of the reproduction cycle.Answer and Explanation: ...
We present five sets of data on genetic architecture of colon and lung cancer susceptibility in mice, humans and rats. They collectively show that the majority of genes for colon and lung cancer susceptibility are linked pair-wise and are likely identical or related. Four CcS/Dem recombinant ...
Studies have shown that the upregulation of UHRF1 expression or enhanced function promotes the epigenetic silencing of tumor suppressor genes (TSGs), thereby facilitating tumor progression and drug resistance in tumors [14, 20, 21]. Studies have shown that UHRF1 expression is increased in CCA ...
1a; Additional file 5) were associated with gene expression of 1549 genes in cis (see Additional file 4c for HOXC4 and PCDHB6 examples). Gene Ontology (GO) analysis of the cis-associated genes showed enrichment for processes involved in neuron differentiation and neuron development (P < ...
In addition to a majority of pseudoautosomal loci, there are genes that are expressed from both the active and the inactive X chromosomes, and which are interspersed among other genes subject to regular dosage compensation. The patterns of X-linked gene expression in different tissues are of ...
sex-linked genes A Qvarnstro¨ m and RI Bailey Department of Ecology and Evolution, Evolutionary Biology Centre, Uppsala University, Norbyva¨gen, Uppsala, Sweden Identification of genes involved in reproductive isolation opens novel ways to investigate links between stages of the speciation process....
Why we age is one of the biggest evolutionary mysteries. The process of natural selection might suggest that people should pass on genes that are advantageous to living longer, thus having more time to reproduce, but there has been no evidence to support this. ...