产品介绍 :The ABLIM1 protein has an N-terminal domain that contains four double zinc finger motifs, which conform to the LIM motif consensus sequence. ABLIM1 binds to F-Actin through a dematin-like domain and is expressed in retina, brain and muscle tissue. There are four known isoforms ...
LIM domain is a unique double-zinc finger motif found in a variety of proteins such as homeodomain transcription factors, kinases, and adaptors. The LIM-containing proteins are involved in diverse biological processes including cytoskeleton organization, cell lineage specification and organ development. ...
Similarity : Contains 1 LIM zinc-binding domain. Contains 1 PDZ (DHR) domain. Database links : UniProtKB/Swiss-Prot: O00151.4 抗体的鉴定: 1)细胞骨架蛋白C端PDLIM1抗体规格抗体的效价鉴定:不管是用于诊断还是用于,制备抗体的目的都是要求较高效价。不同的抗原制备的抗体,要求的效价不一。鉴定效价的方法...
The eukaryotic LIM domain defines a double zinc-finger like structure that functions as a protein-protein interaction module. Whereas in animals the LIM domain is found in numerous proteins of diverse functions, plants possess only a limited number of LIM domain-containing proteins (LIMs). It is...
蛋白别名:PDZ and LIM domain 2 (mystique); PDZ and LIM domain protein 2; PDZ-LIM protein mystique 基因别名:MYSTIQUE; PDLIM2; PP6345; SLIM UniProt ID:(Human) Q96JY6 Entrez Gene ID:(Human) 64236 功能 protein bindingzinc ion bindingfilamin bindingmyosin heavy chain bindingmuscle alpha-actinin...
Fig. 1.FHL1 protein isoforms. (A) LIM domains are composed a two tandem zinc fingers separated by a two amino acid spacer. Each zinc finger contains highly conserved cysteine and histidine residues that coordinate binding to zinc ions to stabilize the domain structure. (B) The humanfhl1gene...
A zinc-finger-containing protein motif that binds the membrane lipid phosphatidylinositol-3-phosphate. The protein that contains FYVE is thereby targeted to the membrane. NMR CHEMICAL SHIFT ANALYSIS Changes in the NMR signature of a protein that are induced on addition of an NMR silent binding part...
LIM (Lin-11, Isl-1, Mec-3), RING (Really interesting new gene), PHD (Plant homology domain) and MYND (myeloid, Nervy, DEAF-1) domains are all zinc-binding domains that ligate two zinc ions. Unlike the better known classical zinc fingers, these domains do not bind DNA, but instead ...
The LIM domain is a modular protein-binding interface LIM domains are zinc-binding protein sequences that are found in a growing number of proteins, including certain transcriptional regulators, proto-oncogene... Karen,L.,Schmeichel,... - 《Cell》 被引量: 976发表: 1994年 Fibronectin-stimulated...
These small proteins contain two protein-interacting LIM domains but little additional sequence, and they seem to function by nucleating the formation of new transcriptional complexes and/or by disrupting existing transcriptional complexes to modulate gene expression programmes. Through these activities, the...