(2010a) Epigenetic repression of PDZ-LIM domain- containing protein 2: Implications for the biology and treatment of breast cancer. J Biol Chem 285: 11786-11792.Qu, Z.; Fu, J.; Yan, P.; Hu, J.; Cheng, S.Y.; Xiao, G. Epigenetic repression of PDZ-LIM domain- containing protein ...
Additionally, its interaction with PDZ-LIM domain-containing protein 2 (PDLIM2) verified circPTPN12’s capability to induce P65 degradation, thereby inhibiting HCC progression. We found circPTPN12 acts as a scaffold, binding ovarian tumor domain-containing 6B (OTUD6B) and PDLIM2, preventing PD...
PDLIM210 is a cytoskeletal and nuclear PDZ-LIM domain protein with important roles in cytoskeleton formation, cell differentiation, signal transduction, and tumorigenesis. PDLIM2 is frequently disrupted in various cancers, and its expression is associated with both tumorigenesis and tumor suppression11....
Previous studies show that PDLIM2, a ubiquitously expressed PDZ-LIM domain-containing protein with high expression in lymphoid tissues and cells including T lymphocytes, is required for the termination of STAT and NF-κB activation [9, 10]. More recent studies suggest that PDLIM2 may function ...
In vitro human cancer cell line studies suggested that the PDZ-LIM domain-containing protein PDLIM2, also known as SLIM or mystique11,12,13, may function as a tumor suppressor14,15,16,17,18,19,20. The main function of PDLIM2 is to promote ubiquitination and proteasomal degradation of nuc...
FHL2 (also known as DRAL or Slim3) is also a LIM-containing protein. FHL2 interacts with both cytoplasmic and nuclear proteins and plays a role in modulation of various cellular processes, such as cell proliferation, transcription, and signal transduction (24). FHL2 is highly expressed in ...
Plant two LIM-domain-containing proteins bind to and stabilize actin filaments that are major constituents in the formation of higher-order actin cytoskeleton. Here, we report that rice LIM-domain protein, OsPLIM2a, is involved in rice tillering likely through actin cytoskeleton organization. OsPLIM...
The eukaryotic LIM domain defines a double zinc-finger like structure that functions as a protein-protein interaction module. Whereas in animals the LIM domain is found in numerous proteins of diverse functions, plants possess only a limited number of LIM domain-containing proteins (LIMs). It is...
别名AW822033; D9Ertd192e; LIM domain-containing protein 1; LIM domains containing 1; LIMD1; LIMD1_HUMAN; OTTHUMP00000164657; OTTHUMP00000210317; rCG_25194. 产品名称 LIM结构域蛋白1抗体说明书 英文名称 Anti-Limd1 货号 YS-K63514 英文名称Anti-Limd1 ...
The LIM and SH3 domain protein family: structural proteins or signal transducers or both? Molecular CancerGrunewald TG, Butt E (2008) The LIM and SH3 domain protein family: structural proteins or signal transducers or both? Mol Cancer 7:31 ... TG Grunewald,E Butt - 《Molecular Cancer》 被...