In addition, most of the major advances in our understanding of non-visual responses to light over the last two decades has been based upon studies in the mouse. In this review, we will summarise the visual and non-visual systems of the laboratory mouse, including the retinal photoreceptors ...
Circadian pace is modulated by light intensity, known as the Aschoff’s rule, with largely unrevealed mechanisms. Here we report that photoreceptor CRY2 mediates blue light input to the circadian clock by directly interacting with clock core component PR
Here, using the retina as a model of the central nervous system, we systemically examine the kinetics of death and neuronal revival. We demonstrate the swift decline of neuronal signalling and identify conditions for reviving synchronous in vivo-like trans-synaptic transmission in postmortem mouse ...
We provide a detailed procedure addressing various environmental variables from housing conditions to data interpretations to successfully set up the test in any laboratory setting and provide representative results. The light–dark box is easy to use and implement. As observed with benzodiazepines and ...
The light/dark test is based on the innate aversion of rodents to brightly illuminated areas and on the spontaneous exploratory behaviour of the animals, applying mild stressors, i.e. novel environment and light. The test apparatus consists of a small dark secure compartment (one-third) and a...
METHODS: To simulate the scenario wherein incisions are infected during surgical procedures as pathogens in the room alight on a wound, MRSA was spread on a defined area of the mouse dorsal skin; the infected skin was then exposed to UVC light (222 nm or 254 nm) followed by a ...
When enabled, it will create an engine-mangle-config.json file in the project root directory with the following format: If there are no special customization needs, keep the default values. By default, all private properties in the engine will be compressed. Advanced usage and field description...
Drosophila larval locomotion consists of forward peristalsis interrupted by episodes of pausing, turning and exploratory behavior (head swinging). This behavior can be regulated by visual input as seen by light-induced increase in pausing, head swinging
Importantly, the secreted IgG3κ showed cryoglobulin-like characteristics and precipitated out of solution as protein crystals at 4 °C in test tube. When the 8A4 hybridoma was grafted to mice, the hybridoma established solid tumors composed of crystal-laden cells; and the mouse IgG3κ mAb ...
Exposure to bright light (2000 lx) for 2 h at the beginning of a 12 h light period (10 lx) resulted in about 1 h advances in the onset and termination of N-acetylserotonin (NAc5HT) synthesis in the pineal gland of NZBWF1 strain mice compared with those in mice not exposed to bright...