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Work in the laboratory of the authors was supported by CEFIPRA (The Indo-French Centre for the Promotion of Advanced Research; programme n°3803), the Human Frontier Science Program (grant RGP26/2007), the ImmuCan programme of the Pôle de Compétitivité Médicen Paris Région, the ...
Single-cell omics is transforming our understanding of cell biology and disease, yet the systems-level analysis and interpretation of single-cell data faces many challenges. In this Perspective, we describe the impact that fundamental concepts from stati
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: The ...
With the rapid advancements in spatial transcriptome sequencing, multiple tissue slices are now available, enabling the integration and interpretation of spatial cellular landscapes. Herein, we introduce SpaDo, a tool for multi-slice spatial domain analy
The Mouse Genomes Project: a repository of inbred laboratory mouse strain genomes Mamm Genome, 26 (2015), pp. 403-412 CrossrefView in ScopusGoogle Scholar 7 International Human Genome Sequencing Consortium Finishing the euchromatic sequence of the human genome Nature, 431 (2004), pp. 931-945 Go...
For cell sorting, 0.5×106/mL cells were resuspended in 1000 mL of PBS with 2% FBS. Then, 2 mL of Band3-APC (Dr. Xiuli An from Laboratory of Membrane Biology, New York Blood Center provided the antibody) was added, and the cells were kept on ice for 20 min. The cells were then...
The biology of three amelanotic melanoma cell lines (Ab, B16F10, and A375) of different species origin was analyzed during in vitro induced melanization in
Finally, the work of Pasteur ushered in the systematic use of laboratory animals for studies of the pathogenesis of infectious diseases, including those caused by viruses. The first viruses were identified as the 19th century ended. Ivanovsky and Beijerinck identified tobacco mosaic virus, and ...
Homeostasis of these different epithelia at the SCJ is regulated by opposing Wnt gradients, and a shift towards a Wnt-repressive microenvironment drives squamous metaplasia. Results Distinct cellular origins of squamous and columnar epithelium To determine the basic cellular features of the mouse endo...