Because DNA ligase joins together DNA fragments in lagging strand synthesis, it has useful applications in genetic engineering. Scientists are able to cut strands of DNA at specific points using restriction enzymes, which are molecules that function like molecular scissors. Then they insert a new pie...
Thus, AKT joins PTEN (phosphatase and tensin homolog deleted from chromosome 10) [66] and fibroblast growth factor receptor 1 (FGFR1) [67], as a substrate for the NEDD4-1 E3 ligase. AKT ubiquitination by NEDD4-1 positively regulates the nuclear trafficking of the activated form of AKT (p...
What enzyme is used to "glue" together the ends of cut pieces of DNA? A. DNA polymerase. B. Restriction enzymes. C. Protease. D. DNA ligase. E. RNA polymerase. DNA Replication Enzymes: A series of enzymes ...
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the gaps or the nicks of DNA and joining Okazaki fragments formed during DNA replication. DNA ligases are highly useful inrecombinant DNA technologyfor the production of the recombinant DNA molecules. DNA ligase joins DNA of interest withvector DNA. Therefore, it is an important enzyme for ...