How does DNA polymerase interact with DNA? How does DNA microarray label DNA pieces? How does DNA ligase work? How does protein synthesis enable DNA to control the cell? How does DNA microarray technology work? How is DNA replication used in biotechnology?
How does DNA ligase work? How is DNA sequencing useful? How does DNA control protein synthesis? What genes are involved in DNA repair? How is DNA stored in eukaryotic cells? What do DNA repair genes do? What are DNA repair genes?
How does it work? In this article, we will look deep into the structure of DNA and explain how it makes itself and how it determines all of your traits. First, let's look at how DNA was discovered. DNA is one of a class of molecules called nucleic acids. Nucleic acids were ...
Ask TaqMan #34 Copy Number Variation – How Does It Work? microRNA Quantification using TaqMan® Advanced miRNA Assays requires a cDNA synthesis step followed by the detection using real-time PCR. The TaqMan Advanced miRNA Assay workflow. ...
OsHCI1, as a RING E3 ligase, is supposed to play an important role in thermal signal regulation. Although it is Golgi-localized, it can be induced by heat shock to enter the nucleus along the cytoskeletal tracts. OsHCI1 interacts with six substrate proteins, including OsbHLH065, and transp...
PCR products are then ligated with T4 DNA ligase. This effectively moves the restriction enzyme sites away from the ends of the fragments and allows efficient digestion. Back to top References Kaufman, D.L. and Evans, G.A. (1990) Restriction endonuclease cleavage at the termini of PCR ...
DNA polymerases were named for their function of catalysing DNA replication, a process that is necessary for growth and propagation of life. DNA involving Watson–Crick base-pairing can be synthesized with high fidelity, the structural and mechanistic or
S. conceptualization; H. S. visualization. Funding and additional information This work was supported by NIH grant R01AAG064227 to C. S. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health....
To achieve inactivation of p53, the FAK FERM domain functions as an adaptor between p53 and the ubiquitin E3 ligase murine double minute-2 (Mdm2), to promote p53 ubiquitination and degradation (Golubovskaya et al., 2005, Lim et al., 2008). In the nucleus, FAK also influences DNA ...
which induces the degradation of histones by proteasomes during spermiogenesis. RNF8 (E3 ubiquitin-protein ligase) is responsible for the ubiquitination of H2A, whereas PHF7 (PHD Finger Protein 7) tags H3K4me3/me2 and H2A for degradation in elongating spermatids. Figure created was adapted from Wang...