Single metal/multiligand catalysis (SMMLC) has recently been developed for the highly efficient and selective synthesis of valuable compounds. As a newly emerged member of SMMLC, ligand relay catalysis (LRC) injects new vitality into this concept, featuring good tunability, operational simplicity, ...
However, effective strategies established, such as cooperative catalysis, synergistic catalysis, sequential/relay catalysis, cannot avoid the incompatibility of catalysts, substrates, intermediates and solvents is the main challenge. Herein, we developed a novel strategy, wherein a single functional molecule...
In conventional homogeneous catalysis, supporting ligands act as spectators that do not interact directly with substrates. However, in metal–ligand cooperative catalysis, ligands are involved in facilitating reaction pathways that would be less favourab
Nucleophilic amino acids make important contributions to protein function, including performing key roles in catalysis and serving as sites for post-translational modification. Electrophilic groups that target amino-acid nucleophiles have been used to create covalent ligands and drugs, but have, so far,...
In asymmetric catalysis, axially chiral ligands hold a unique place among privileged ligand structures such as BINOL, BINAP and their derivatives.21,22 In spite of the many potential uses mentioned, the application of 1,8-diarylnaphthalene based scaffolds as ligands in asymmetric catalysis is relativ...
Mechanistic studies suggest that, distinct from palladium catalysis under thermal condition, irradiation-induced palladium catalysis involves irradiation-induced single-electron transfer and dynamic ligand-dissociation/association process to allow two phosphine ligand to work synergistically....
Sequential double hydrofunctionalizationalization of alkynes is a powerful method to construct useful vicinal compounds. Herein, we report a cobalt-catalyzed sequential hydrosilylation/hydrohydrazidation of alkynes to afford 1,2-compounds via ligand relay catalysis. A phenomenon of ligand relay is found...
Ligand relay catalysisDifunctionalizationStyreneAlkoxysilaneHydroaminationDiazo compoundsHere, we report a cobalt-catalyzed sequential dehydrogenative Heck silylation/hydroamination of styrenes with hydrosilane and diazo compound to access 1-amino-2-silyl compounds with excellent regioselectivity. Th...
(mainゞroup metals, transition metals, and rare〆arth metals), a truly broad scope of asymmetric reactions (more than 50 types), diverse areas of catalysis (organocatalysis, Lewis゛cid catalysis, bimetallic relay catalysis, and photocatalysis), numerous synthetic applications of bioactive compounds, ...
Notably, this rapid, homogeneous CO2 reduction catalysis is achieved without any modifications to the secondary coordination sphere to introduce hydrogen bond/proton-relay functionalities to break electronic scaling relationships. Finally, to assess the long-term catalytic stability and recyclability of [Fe1...