ENPP1/CD203a is a membrane-bound ectonucleotidase capable of hydrolyzing ATP, cGAMP and other substrates. Its enzymatic activity plays an important role in the balance of extracellular adenine nucleotides and the modulation of purinergic signaling, in soft tissue calcification, and in the regulation ...
We then determined cell viability using an ATP detection kit. Notably, PC accumulation inhibited PDO cell viability in a dose-dependent manner (Fig. 8A, B). Subsequently, we performed H&E staining (Fig. 8C) and Ki67 IHC analysis on PDO models treated with or without 60 mM PC. The ...
michaelgoadHealthcare and Life Sciences Blog Feb 01, 2025 8 MIN READ Image Search Series Part 1: Chest X-ray lookup with MedImageInsight @Alberto Santamaria-Pang, Principal Applied Data Scientist, HLS AI and Adjunct Faculty at Johns Hopkins Medicine @Asma Ben Abacha, Senion Applied Scientist,...
Updated August 2023. Download In vivo Monoclonal Antibodies Discover the latest addition to the Assay Genie portfolio: monoclonal in vivo antibodies. These functional grade antibodies can be used for co-stimulation, blocking, neutralization or cell depletion and are validated for ELISA, flow cytometry,...
2023, Science Advances Intratumor Heterogeneity and Treatment Resistance of Solid Tumors with a Focus on Polyploid/Senescent Giant Cancer Cells (PGCCs) 2023, International Journal of Molecular Sciences High-Risk Oncogenic Human Cytomegalovirus 2022, Viruses Oncogenic and Stemness Signatures of the High-Ri...
There is no boundary to the development of biotechnology and life sciences which are closely linked with human survival and indispensable to people's daily life. Search Poloxamer 188 Safeguards Isolated Grown-up Mouse Cardiomyocytes through Reoxygenation Injury ...
cause neurotoxicity while suppressing tumor progression through the interaction with Smad4, WW domain-containing oxidoreductase (WWOX) and p53. Neurotoxicity can also be caused by the formation of TIAF1-Aβ complex.ADAM10a disintegrin and metalloproteinase 10,AMPARAMPA receptor,APPamyloid precursor protein...
(age ranges 16–36 years, grade I ~ II) with acute lumbar disc herniation or adolescent idiopathic scoliosis but without IDD. The degenerated NP were obtained from 10 patients (age ranges 45–70 years, grade III ~ V) with IVDD. The degenerated degree of IDD was assessed by ...
Diabetes.World Health Organizationhttps://www.who.int/news-room/fact-sheets/detail/diabetes(2023). Ahechu, P. et al. NLRP3 inflammasome: a possible link between obesity-associated low-grade chronic inflammation and colorectal cancer development.Front Immunol.9, 2918 (2018). ...
The bioactive components of EOs may have several cellular targets including inhibition of ATP production, cell wall and cell membrane damage, cytoplasmic coagulation, and alteration of ion transport [146] (Figure 6). Figure 6. Schematic illustration of the mechanisms of antimicrobial activities of ...