ENPP1/CD203a is a membrane-bound ectonucleotidase capable of hydrolyzing ATP, cGAMP and other substrates. Its enzymatic activity plays an important role in the balance of extracellular adenine nucleotides and the modulation of purinergic signaling, in soft tissue calcification, and in the regulation ...
Pietrus M, Pitynski K, Waligora M, Milian-Ciesielska K, Ludwin A, Socha MW et al (2023) Association of membranous WNT-1 and nuclear mTOR with endometrial cancer grade. Int J Mol Sci 24:8342. https://doi.org/10.3390/ijms24098342 Article PubMed PubMed Central Google Scholar Devis-...
Hi everyone Can someone help me find the right sources to get started with the bachelor and Masters in Health and Lifesciences? Thank you SASSA and Health: A Brief Overview SASSA (South African Social Security Agency) plays a crucial role in supporting the health and well-being of vulnerable...
Kiffin R, Segura-Aguilar J, Cuervo AM, Glimcher LH, Hetz C (2012) Targeting the UPR transcription factor XBP1 protects against Huntington’s disease through the regulation of FoxO1 and autophagy. Hum Mol Genet 21(10):2245–2262
cause neurotoxicity while suppressing tumor progression through the interaction with Smad4, WW domain-containing oxidoreductase (WWOX) and p53. Neurotoxicity can also be caused by the formation of TIAF1-Aβ complex.ADAM10a disintegrin and metalloproteinase 10,AMPARAMPA receptor,APPamyloid precursor protein...
(age ranges 16–36 years, grade I ~ II) with acute lumbar disc herniation or adolescent idiopathic scoliosis but without IDD. The degenerated NP were obtained from 10 patients (age ranges 45–70 years, grade III ~ V) with IVDD. The degenerated degree of IDD was assessed by ...
diversity of plant kingdom. The sequences were analyzed using the ConSurf [46,47] and Gremlin [48,49] servers. We then selected residues that contribute to the central cavity, are not fully conserved (ConSurf grade ≤ 8), and display variability that could not be readily explained by...
attending the fifth grade. A total of 1005 individuals were examined, which constituted 85% of the selected population. Their average age was 11.9 ± 0.11 years. Over 32 years of prospective study, 7 medical examinations were carried out at different intervals. Our study participants were represen...
foreign bodies or infection and restores homeostasis and initiates repair. The acute pro-inflammatory state is vital for the repair of cells but too much for too long is thought to be detrimental; for example chronic low grade inflammation has been associated with ageing and has been implicated ...
MTSS1 is a ubiquitously expressed intracellular protein known mainly for its involvement in basic cellular processes, such as the regulation of actin organ