. The beta chain encoded by ITGB2 can combine with multiple alpha partners to give rise to different integrins—e.g., with the alpha L chain to form the integrin LFA-1, or with the alpha M chain to form the integrin Mac-1. Integrins participate in cell adhesion as well as cell ...
品名 小鼠淋巴细胞功能相关抗原1(LFA-1)elisa检测试剂盒 货号 ZK-5240 产地 上海 厂商 上海臻科生物科技有限公司 单位 盒 规格 48T 保存 2-8℃冷藏 特色服务 提供免费代测 酶标板 12孔*4条 注意事项 严格按照说明书操作 标准品 0.3mL*6管 独特优势 灵敏度高,特异性强,重复性好 保质期 6...
LFA-1 General Information APPROVED SYMBOL ITGAL APPROVED NAME integrin subunit alpha L HGNC ID HGNC:6148 SYNONYMS antigen CD11A (p180), LFA-1, lymphocyte function-associated antigen 1, alpha polypeptide LOCUS TYPE gene with protein product
《LFA-1(CD11a)在类风湿性关节炎发生、发展中的作用机制研究》是依托吉林大学，由柳忠辉担任项目负责人的面上项目。项目摘要 类风湿性关节炎（RA），是一种典型的多因素诱发的自身免疫性疾病。近年来黏附分子在RA疾病发展进程中的作用受到普遍关注，尤其是LFA-1 /ICAM-1可以促进炎症细胞的粘附及趋化...
产品名称:小鼠淋巴细胞功能相关抗原1(LFA-1)ELISA试剂盒免费代测 特强 英文名称:MouseLymphocyteFunctionRelatedAntigen1(LFA-1)ELISAKit 检测方法:酶联免疫法 品牌:佰利莱 货号:BLL-S7613G 检测指标:LFA-1 标记物:HRP标记物 应用:定性/定量/酶活检测 贮藏条件:2-8℃ 有效期:6个月 种属:大鼠、小鼠、人、鸡...
Precise spatiotemporal regulation of leukocyte extravasation is key for generating an efficient immune response to injury or infection. The integrins LFA-1(CD11a/CD18) and Mac-1(CD11b/CD18) play overlapping roles in neutrophil migration because they bind
Lifitegrast, an LFA-1 antagonist that blocks binding of ICAM-1 to LFA-1, has recently been approved in the United States for the treatment of signs and symptoms of DED. In this review, we evaluate research findings to explore the potential role of LFA-1/ICAM-1 interaction in the ...
VVN001作为新一代LFA-1(淋巴细胞功能相关抗原1)拮抗剂,能够高效阻断LFA-1与配体ICAM-1(细胞间粘附分子1)的结合,减少眼部炎症反应。通过抑制T细胞的迁移和激活,VVN001能够减少眼部炎症反应,保护眼表组织,特别是角膜、结膜和泪腺,免受炎症性损伤。 目前VVN001滴眼液已进入III期临床试验阶段,以下是关于VVN001滴眼液的临...
Our results primarily suggested that LFA-1 gene polymorphisms may predict the sporadic breast IDC risk and prognosis factors in Chinese Han women in Heilongjiang Province. 展开 关键词: Lymphocyte function-associated antigen-1 Infiltrative duct carcinoma Polymorphisms Haplotype ...