Kurata T, Micksche M (1978) Correlation of immune response with clinical stage in Lewis lung tumor-bearing mice. Oncology 35:155KURATA, T. & MICKSCHE, M. (1978). Correlation of immune response with clinical stage in Lewis lung tumor-bearing mice. Oncology, 35, 155 - 159....
Objective To investigate the mechanism of tumour-suppressive effect and apoptosis of Zilongjin Tablets combined with icotinib through epidermal growth factor receptor (EGFR)/phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt) pathway in tumor-bearing mice.Methods Lewis lung cancer mouse model wa...
The purpose of the current study was to investigate the effect of the dosing time on the pharmacokinetics of erlotinib and the circadian rhythms of the metabolism enzymes in tumor-bearing mice. Female C57BL mice were randomly assigned to six groups. Erlotinib was orally administrated to the mice...
关键词 玉屏风颗粒;上皮-间充质转化;上皮屏障;肿瘤转移;β-连环蛋白 Effects of Yupingfeng granules on tumor metastasis of Lewis tumor-bearing mice by adjusting the EMT LIN Yingxue1,CUI Haipeng2,WANG Lingdi1,YANG Changshuo3,ZHUANG Pengwei(3 1. Dept. of Pharmacy,the Affiliated Hospital of ...
Effects of Yupingfeng granules on tumor metastasis of Lewis tumor -bearing mice by adjusting the EMT LIN Yingxue 1，CUI Haipeng 2，WANG Lingdi 1，YANG Changshuo 3，ZHUANG Pengwei 3（1. Dept. of Pharmacy ，the Affiliated Hospital of Chengde Medical University ，Hebei Chengde 067000...
Organism TypeMouseATCC# CLR1642: Cell line established from the lung of a C57BL mouse bearing a tumor resulting from an implantation of primary Lewis lung carcinoma. The cells are resistant to 1,3-bis-(2-chloroethyl)-1-nitrosourea, but are sensitive to methotrexate. The cells are reported to...
tumordoi:10.1002/jlb.42.6.682M. Rita YoungRoger A. EndicottG. Patrick DuffieH. Terry WepsicJohn Wiley & Sons, LtdJournal of Leukocyte BiologyYoung,MR,Endicott,RA,Duffie,GP,Wepsic,HT.Suppressor alveolar macrophages in mice bearing metastatic Lewis lung carcinoma tumors. Journal of Leukocyte ...
Objection:ABSTRACTTostudytheantitumoreffectsandsideeffectsoferlotinibwithdifferentdosingtimeinLewistumor-bearingmice,andinvestigateitsunderlyingmechanismviaEGFR-AKT-CyclinD—CDK-4pathway.Methods:1.ThemousemodelofLewislungcancerxenograftswasestablished.Theanimalswererandomlydividedintothreedosegroups(15,30,60mg・ kg。
drugs were given to each gr oup in order to observe the d aily life and the tumor growing status of the mice.D etermination of the cell apop- tosis in the tumorous tissue was perform ed by T UNE L method.[Results 】The general status of the Lewis tumor-bearing mice could be im·...
The maximum concentration of Ml in the tumor was observed at 2 h posttreatment, while the maxima in the plasma and liver were observed at 15 min. On the other hand, i.v. injection of M1 into mice showed a weaker antitumor effect than ME2303 injection, though Ml levels in the plasma ...