enters the fetus, and is metabolized. Carbidopa concentrations in fetal tissue appeared to be minimal. Use of SINEMET in women of childbearing potential requires that the anticipated benefits of the drug be weighed against possible
There are no human studies that have examined the effects of Sinemet on a fetus. In prescribing Sinemet for a pregnant woman, the treating physician must weigh the potential risks to the fetus against the potential benefits to the mother. Levodopa is distributed intobreast milk. It also may in...
Levodopa-induced dyskinesia (LID) can be improved by adjusting the dosage to find a tolerable balance between the benefits and side effects. LID fluctuates in severity throughout the day but there is no reliable way of objectively monitoring patients at home. The intervention is ClearSky's LID-...
7.Some patients get small benefits from carbidopa/levodopa, a combination of drugs prescribed for patients with Parkinson’s disease, but most don’t. 8.In particular, researchers zeroed in on patients who were administered the drug levodopa, also called L-dopa, which is used to treat Parkinson...
The developmental and health benefits of breastfeeding should be considered along with the mother’s clinical need for DUOPA and any potential adverse effects on the breastfed infant from DUOPA or from the underlying maternal condition. ...
Recent data have suggested that levodopa can either slow down the progression of Parkinson disease and/or have increased benefits even after drug administration has stopped. A common off-label use for levodopa is restless leg syndrome and periodic limb movement in sleep (PLMS). Levodopa has been ...
Use of carbidopa and levodopa extended-release in women of childbearing potential requires that the anticipated benefits of the drug be weighed against possible hazards to mother and child. Nursing Mothers Levodopa has been detected in human milk. Caution should be exercised when carbidopa and ...
Although levodopa has provided a major advance in the treatment of parkinsonism, its maximum benefits have not yet been realised, in part because of its complicated pharmacokinetics. This review summarises the available pharmacokinetic data involving levodopa, especially as it relates to therapeutic respo...
Use caution in nursing women. Consider known benefits of breast-feeding along with mother's clinical need for the drug and any potential adverse effects on the infant from drug or underlying maternal condition.Pediatric UseSafety and efficacy not established in children <18 years of age....
Use of carbidopa and levodopa tablets in women of childbearing potential requires that the anticipated benefits of the drug be weighed against possible hazards to mother and child. Nursing Mothers Levodopa has been detected in human milk. Caution should be exercised when carbidopa and levodopa tablets...