Initial detection utilized chest X-ray or echocardiogram, leading to subsequent diagnoses based on pericardial effusion and/or bone marrow examination. Two patients received chemotherapy at the time of initial diagnosis, one with cytarabine and etoposide, and the other with cytarabine...
Bone marrow examination: hypercellularity, myeloid bulge with sequential orderly maturation, increase eosinophilic and basophilic series, increased megakaryocytes. Blood or bone marrow contain less than 10% leukemic blasts. There may be myelofibrosis. Gaucher like cells or sea-blue histiocytes may...
Bone marrow examination revealed extensive marrow involvement in both cases. Serum EBV viral loads at diagnosis of these two patients were at 130,000 and 60,000 copies/渭L, respectively. Staging workup including nasal examination/biopsy was negative. Both patients passed away in a month. These ...
These entities can be best discriminated by pathologic examination of the spleen; in the absence of a splenectomy specimen, bone marrow examination shows characteristic features in SDRPL with a predominant intrasinusoidal pattern, while SMZL and SBLPN have a more diverse growth pattern in the bone ...
At age 23, after an episode of anaphylactic shock, a bone marrow examination revealed mast cell leukemia. She ultimately died despite aggressive chemotherapy and bone marrow transplantation.doi:10.1111/j.1525-1470.2011.01650.xRattanavalai Chantorn...
Furthermore, micro-computed tomography (μ-CT) examination showed that cortical wall thickness, as well as trabecular bone volume, decreased in leukemic animals (Figure 1g). Decreased trabecular bone volume resulted in a larger trabecular area in leukemic animals (Figures 1f and g). These data ...
Little is known about how leukemia cells alter the bone marrow (BM) niche to facilitate their own growth and evade chemotherapy. Here, we provide evidence that acute myeloid leukemia (AML) blasts remodel the BM niche into a leukemia growth-permissive and
With acute leukemia, immature white blood cells multiply quickly in the bone marrow. Over time, they crowd out healthy cells. (Patients may notice that they bleed a lot or suffer from infections as a result.) When these cells reach high numbers, they can sometimes spread to other organs, ...
26、ia and hypocalcemia etc.,Acute Leukemia,Laboratory Findings Blood Routine Examination 1) WBC count 2)leukemic cells can be found in 90% patients,Acute Leukemia,Bone Marrow Aspiration 1)Cellularity . found in 90% patients . 2)Leukemic cells 30% nonerythroid cells 3) Auer rods (spindle-shap...
primary (de novo) and secondary AML; the latter was further subdivided into AML with MDS-related changes, AML following MPN, chronic myelomonocytic leukemia (CMML) or MDS/MPN, and therapy-related AML. In all instances, bone marrow examination and cytogenetic studies were performed or reviewed at...