Hybridizing dna of first length to capture probes at site, hybridizing dna of second length to capture probes at another site, observing fluorescent signals as potential is reversed, detecting sites which dehybridize at a potential... MJ Heller,RG Sosnowski - US 被引量: 139发表: 2001年 Chromos...
The distribution of lengths of single-strand DNA in Chinese hamster ovary cells in the G1 phase of the cell cycle has been observed for various conditions of cell lysis and incubation of the lysates. The method of analysis was band sedimentation through a self-generating density gradient, a te...
Telomere length as a marker of DNA damagedoi:10.1055/s-0042-1757054Slezko, AFrank-Herrmann, PZimmer, JStrowitzki, TKrivega, MGeburtshilfe und Frauenheilkunde
In vertebrates, segment identity and number are determined embryonically. During the process of main body axis segmentation, the embryonic segments—somites—form rhythmically from anterior to posterior as the embryo elongates. As somite formation proceeds, the unsegmented presomitic mesoderm (PSM) shrink...
Telomeres are environment-sensitive regulators of health and aging. Here,we present telomere DNA length analysis of two reef-building coral genera revealing that the long- and short-term water thermal regime is a key driver of between-colony variation ac
The conclusions drawn provide a better understanding of the Arabidopsis genome and how the gene transcripts are processed. The results also allow better predictions to be made for, as yet, poorly defined genes and provide a reference for comparisons with other plant genomes whose complete sequences...
aThe helix axis of DNA in vivo is usually curved, rather than linear. This is a necessary condition, as the stretched length of the human genome is about 1 meter and this length needs to be "packaged" in order to fit in the nucleus of a cell. In eukaryotes, nature solved this ...
However, all other homologues did bind to ds-DNA strongly, with the binding affinities increasing as a function of the number of repeating pyrrole carboxamide units, implying that a hydrogen bond donor or acceptor atom per se at the N-terminus is not essential for their DNA binding. Studies ...
DNA based on the X-ray crystal structure of the bacterial XPD family helicase DinG in complex with the DNA32. This model revealed that methionine 492 (M492) is buried within the core of the helicase domain in proximity to the single-stranded DNA binding site of the protein, making ...
S-phase length is determined by DNA synthesis rate, which depends on the number of active replication forks and their velocity. Here, we show that E2F-dependent transcription, through E2F6, determines the replication capacity of a cell, defined as the maximal amount of DNA a cell can ...