Lack of exercise. Not getting enough physical activity can cause you to gain weight, which increases your risk for high cholesterol. High body weight. Being overweight or having obesity can bring up your cholesterol levels. Tobacco use. Cigarettes and other tobacco products (including vapes) lower...
In patients with a guideline indication for statin therapy, those with chart‐documented LDL‐C testing in the prior 2 years had lower core laboratory LDL‐C levels at the time of enrollment than those without (median 9...
Methods: We retrospectively identified patients within the UCHealth electronic health record among adults from 2012 to 2023 prescribed a statin with at least 3 LDL levels. Patients prescribed concomitant lipid-lowering agents were excluded. We performed a multivariate linear regression model to predict ...
The causal relation between elevated levels of LDL-C and cardiovascular disease has been largely established by experimental and clinical studies. Thus, the reduction of LDL-C levels is a major target for the prevention of cardiovascular disease. In the last decades, statins have been used as the...
METHODS: In a double-blind, randomized crossover study, 15 obese diet-treated T2D patients received cerivastatin (0.4 mg/day) or placebo for 3 months. Circulating ox-LDL levels were measured fasting and during a euglycaemic-hyperinsulinaemic clamp (approximately 5.5 mmol/l; EHC) and a ...
Baseline levels are from the more intensive treatment group. The solid line represents the meta-regression slope of the change in rate ratio for treatment across increasing levels of baseline LDL-C. Results do not change when using baseline LDL-C values from the less intensive treament group. ...
2b, w3: −20%, lPev =el 0s.i0n12ti;mwe6:u−po1n6%L,PPA =1/3 0i.n0h1i7b)i.tFiounr,thwearsasniganlyisfiiscaonfttlhyelosewreurmcolimpopparroedtetino content at the experimental endpoint showed a trend towards decreased LDL levels for the Ki16425...
In PROSPER, women, but not men, with the A allele had higher LDL-C levels than those who did not. Additionally, following randomization to the pravastatin arm of the study (40 mg/day), women homozygous for the A allele displayed greater reduction in LDL-C than those with the G allele....
We tested for association between the APOE polymorphism and LDL-C concentration using the model 1 and model 2 adjustment strategies. As a previous study of this population noted the APOE-sex interaction on circulating lipid levels (36), all analyses incorporated such interaction. The frequencies of...
This may suggest that the elastic property of the arterial wall is good for preventing atherosclerotic disease. Moreover, we can also know that the places of high levels of LDL uptake coincided with the regions of low wall shear stress; the thickened arterial wall can decrease the uptake of ...