在没有心血管风险的一般人群中,降低LDL-c 疗法可能会带来寿命益处。 2022年:Association of low-density lipoprotein cholesterol levels with the risk of mortality and cardiovascular events: A meta-analysis of cohort studies with 1,232,694 participants(低密度脂蛋白胆固醇...
在没有任何先前的心血管疾病或糖尿病的个体中，有72.1％的患者，LDL水平低于130 mg / dL，这个数值是普通意义上非常优秀且心血管风险非常低的参考了。LDL普通意义上的参考范围 甚至，有近一半的患者，LDL达到了低于100 mg / dL的最佳水平。close to half had LDL levels classified inguidelines as optimal (le...
LDL-C makes up the majority of the body’s cholesterol. WhenLDL-Clevels are high in the bloodstream, cholesterol/plaque may build up in the wall of the artery, resulting in a progressive disease called atherosclerosis. As a rule, you want to keep your LDLcholesterol low. ...
LDL-Cholesterol Lowering for the Primary Prevention of Cardiovascular Disease Among Men with Primary Elevations of LDL-Cholesterol Levels of 190 mg/dL or Above: Analyses from the WOSCOPS 5-year Randomised Trial and 20-year Observational Follow-Up.Circulation. 2017;136:1878-1891....
[10] Luo Z, Huang Z, Sun F, et al. The clinical effects of inclisiran, a first-in-class LDL-C lowering siRNA therapy, on the LDL-C levels in Chinese patients with hypercholesterolemia. J Clin Lipidol. 2023;17(3):392-400. doi:10.1016/j.jacl.2023.04.010 ...
5. Sillesen H, Amarenco P, Hennerici MG, et al. Atorvastatin reduces the risk of cardiovascular events in patients with carotid atherosclerosis: a secondary analysis of the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) ...
The high egg diet certainly represents a significant cholesterol load. An egg contains between 250 and 550 mg of cholesterol and thus our patients imbibed over 7,000 mg of cholesterol per day. Contrary to expectations, serum cholesterol and lipoprotein levels remained normal throughout the period ...
Thus, in most persons with normal or mildly elevated serum cholesterol levels, lipid-lowering therapies are likely to produce progressively less benefit in terms of reducing the rate of coronary events.text editorEmerging Infectious Diseases
The main goal of a treatment program is to lower total cholesterol levels, LDL ("bad") cholesterol levels, and triglyceride levels. Treatment may cause a slight rise in HDL or good cholesterol in the blood. There are two main ways to control cholesterol; ...
7.Manemann SM, et al. Variability in Lipid Levels and Risk for Cardiovascular Disease: An Electronic Health Record-Based Population Cohort Study. J Am Heart Assoc. 2023;12(5):e027639. 8.Robert A Byrne, et al. 2023 ESC Guidelines for the management of acute coronary syndromes. Eur Heart...