在没有心血管风险的一般人群中,降低LDL-c 疗法可能会带来寿命益处。 2022年:Association of low-density lipoprotein cholesterol levels with the risk of mortality and cardiovascular events: A meta-analysis of cohort studies with 1,232,694 participants(低密度脂蛋白胆固醇...
Achieving these cholesterol target levels did not confer any additional benefit in a systematic review of 35 randomised controlled trials. Recommending cholesterol lowering treatment based on estimated cardiovascular risk fails to identify many high-risk patients and may lead to unnecessary treatment of low...
In patients with severe primary hypercholesterolemia (LDL-C level ≥190 mg/dL [≥4.9 mmol/L]), without calculating 10-year ASCVD risk, begin high-intensity statin therapy. LDL-C>=4.9mmol/L的重度原发性高胆固醇患者,无需计算未来10年心脑血管疾病风险,直接启动高强度他汀降脂治疗。
InflammationOsteophytesObjective: A relation between osteoarthritis (OA) and increased cholesterol levels is apparent. In the present study we investigate OA pathology in apolipoprotein E (ApoE)(-/-) mice with and without a cholesterol-rich diet, a model for high systemic low density lipoprotein (...
[13]. Ray KK, et al. Long-term efficacy and safety of inclisiran in patients with high cardiovascular risk and elevated LDL cholesterol (ORION-3): results from the 4-year open-label extension of the ORION-1 ...
Your LDL cholesterol levels have five categories: optimal, near optimal, borderline high, high and very high. A measurement of 130 to 159 milligrams per deciliter places you in the range of borderline high, an area which may pose a health risk depending on the number of risk factors you ha...
no link to heart disease and LDL cholesterol – but there werehints that those with higher levels survived longer.60岁以上的老人，LDL-C和死亡率反相关，这个结论和传统的胆固醇假说（胆固醇，LDL-C导致动脉粥样硬化）完全不一致。High LDL-C is inversely associated withmortality in most people over 60...
13.Ray KK, et al. Long-term efficacy and safety of inclisiran in patients with high cardiovascular risk and elevated LDL cholesterol (ORION-3): results from the 4-year open-label extension of the ORION-1 trial. Lancet Diabetes Endocrinol. 2023 Feb;11(2):109-119. ...
Cholesterol is naturally in the body; however, a diet high in fat and sugar; lack of exercise, and obesity contribute to elevated LDL or bad cholesterol levels in the blood. There are no symptoms of high cholesterol. You can lower your cholesterol with d
Plaque Formation in Arteries: High levels of LDL cholesterol in the bloodstream can lead to formation of "plaques" in the arteries. What are the potential health consequences of coronary arteries being clogged by "plaques"? Name some specific foods that...