Symmetry C8 3.0mmx15cm at 0.4 ml/min: Water: ACN gradient; 85% to 36% at 45 minutes: PDA scan: 220-400 nm: MS scan: 50-500 mz The answer is it depends on the goal of the experiment 微柱是指: 10-5 - 10-6 torr的压力指的是分析器还是离子源的压力? Di 是什么东西? 为什么要提...
amuLCMS液质联用资料系列 +++++++++---+++++---Adducts Clusters formed in LC/MS Adduct*/Adduct Ion FormedCauseIonicAPCIESI+/-m/z of IonLithium[M+Li]Ammonia[M + NH4]Water[M + H3O]Sodium[M + Na]Lithium SaltsAmmonia/NH4OHWater/AcidsSodium salts IonicAdductAdduct Ionic[M + H + 6]...
TurboIonSpray-IonSpray(pneumaticallyassistedElectrospray)optionwhichutilizesaheatedauxiliarygasflow.HeatedNebulizer-AtmosphericPressureChemicalIonization(APCI)sourcewhichionizescompoundsinthegasphase.第2页/共33页 IonEvaporationandFormation ++- +++ +- ++ + +--++ -+++++-+-+ ++ + + +++- ++ 第3页/共...
Common CID Losses Even Losses (M+X)+- 2 hydrogen molecule (M+X)+- H2 (M+X)+- 18 water (M+X)+- H2O (M+X)+- 20 hydrogen fluoride (M+X)+- HF (M+X)+- 28 CO or ethylene (M+X)+- CO or (M+X)+- C2H2 (M+X)+- 30 formaldehyde (M+X)+- H2CO (M+X)+- 31 ...
Just one round of comprehensive optimization maximizes sensitivity, taking into consideration polarity, adduct ions, valency etc. The results of this process can be viewed on a graph using the data browser function. The MRM optimization results screen simultaneously displays a chromatogram...
•Elucidatedrugdegradationpathwaytosupportexcipientselectionandformulationdevelopment •ConfirmpeakidentityforDSandrelatedsubstances •SupportQAissuesandNDA •SupportManufacturingprocessandfinisheddrugproducts FeaturesofLC/MS Advantages:HighsensitivityHighselectivitySpeedCombinedpowerofseparationandidentificationMolecularweight...