aHuman Cartilage Repair with a Photoreactive Adhesive-Hydrogel Composite 人的软骨修理与Photoreactive胶粘剂水凝胶综合[translate] aSelf-Assembly of Large and Small Molecules into Hierarchically Ordered Sacs and Membranes 大和小分子自已汇编到等级制度被命令的囊和膜里[translate]...
The data indicate that small molecules with high turnover rates (up to 25% h −1) may occasionally be excreted by phytoplankton cells. The turnover time of high molecular weight excreted compounds is much longer. A correlation is found between the rate of production of these large ...
The discovery of captopril: from large animals to small molecules Opie, L. H., Kowolik, H., The discovery of captopril: from large animals to small molecules. Cardiovasc. Res. 1995, 30, 18-25... LH Opie,H Kowolik - 《Cardiovascular Research》 被引量: 46发表: 1995年 Successful Appli...
Scott, D. E., Bayly, A. R., Abell, C. & Skidmore, J. Small molecules, big targets: drug discovery faces the protein–protein interaction challenge.Nat. Rev. Drug Discov.15, 533–550 (2016). ArticleCAS Davey, N. E., Cyert, M. S. & Moses, A. M. Short linear motifs – ex n...
This requires assumptions on the permeability which are not straight forward and difficult to check with independent methods, especially if permeability of small molecules like water is concerned. In contrast, volume changes are higher order effects in small deformation measurements and no assumptions on...
Notwithstanding the success of existing methods to recognize similar pockets, many of these algorithms perform well only against the experimental structures of proteins complexed with small molecules. Utilizing datasets of target structures with predicted binding sites poses a formidable challenge for pocket...
🔬Molecule-oriented instructions:This component delves into the world of small molecules, emphasizing their inherent properties and behaviors. It sheds light on the fundamental challenges of diverse chemical reactions and molecular design, with 148,4K instructions across six tasks. ...
Evidence from other techniques suggests that the excluded material is of different structures from that of the resolved material rather than consisting of aggregates of small molecules. We speculate that the excluded material may elute early because the structures of this material are three-dimensional...
Increasing numbers of protein interactions have been identified in high-throughput experiments, but only a small proportion have solved structures. Recently, sequence coevolution-based approaches have led to a breakthrough in predicting monomer protein s
We benchmark Allegro’s ability to accurately learn energies and forces of small molecules on the revised MD-17 dataset43, a recomputed version of the original MD-17 dataset10,44,45that contains ten small, organic molecules at DFT accuracy. As shown in Table1, Allegro obtains state-of-the...