Large granular lymphocyte (LGL) leukemia is a rare lymphoproliferative malignancy that arises from either CD3+ mature cytotoxic T-cell or CD3- natural killer (NK)-cell lineage. It is a heterogeneous disorder due to distinct morphological, immunophenotypical, and clinical features among patients, ...
T-cell large granular lymphocytic leukemia and plasma cell disorders. Haematologica. 2019;104:e108–10. Article PubMed PubMed Central Google Scholar Sokol L, Loughran TP Jr. Large granular lymphocyte leukemia. Oncologist. 2006;11:263–73. Article CAS PubMed Google Scholar Komrokji RS, Ali ...
T-cell and natural killer-cell large granular lymphocyte leukemia neoplasias. Large granular lymphocyte (LGL) leukemia is a rare disorder of cytotoxic lymphocytes. LGL cells play an integral role in the immune system and are divided ... RJ Watters,X Liu,TP Loughran - 《Leukemia & Lymphoma》 ...
Large granular lymphocyte (LGL) leukemia is a rare disorder of mature cytotoxic T or natural killer cells. Large granular lymphocyte leukemia is characterized by the accumulation of cytotoxic cells in blood and infiltration in the bone marrow, liver, and spleen. Herein, we review clinical features...
Composite lymphocyte-rich thymoma and peripheral T cell lymphoma not otherwise specified: cased report and literature review Lab Med (43) (2012), pp. 4-8 Google Scholar [13] H. Sun, S. Wei, L. Yang Dysfunction of immune system in the development of large granular lymphocyte leukemia Hematol...
Epstein-Barr virus-asso⁃ ciated natural killer-large granular lymphocyte leukemia[J]. Hum Pathol, 1994, 25(9):953-960.Gelb AB;van de Rijn M;Regula DJ;.Epstein-Barr virus-associated natural killer-large granular lymphocyte leukemia.Hum Pathol.1994.953-960...
The large granular lymphocyte of the rat, the effector cell of natural killer (NK) activity, possesses specific antigenic markers which allow one to use them to identify the normal and neoplastic LGL...doi:10.1007/978-3-642-84110-1_30Ward, Jerrold M....
lymphocyte (redirected fromlarge granular lymphocyte) Thesaurus Medical Acronyms Encyclopedia lym·pho·cyte (lĭm′fə-sīt′) n. Any of a class of white blood cells of the vertebrate immune system, including the B cells, T cells, and natural killer cells, that in mammals derive from a ...
Large granular lymphocyte leukemia (LGLL) is a rare lymphoproliferative disorder characterized by the clonal expansion of cytotoxic T-LGL or NK cells. Chronic isolated neutropenia represents the clinical hallmark of the disease, being present in up to 80% of cases. New advances were made in the ...
Immunophenotypic analysis indicated the lymphocytes were CD3+, CD8+ T expressing the alpha receptor and a leukointegrin, alpha d. Chemotherapy and splenectomy resulted in an initial reduction in the lymphocyte count.关键词: leukemia, T-lymphocytes, drug therapy, dogs, case studies, splenectomy ...