Composite lymphomaBackground: Evolution of indolent to aggressive lymphoma has been described in dogs but is difficult to distinguish from the de novo development of a second, clonally distinct lymphoma. Differentiation of these scenarios can be aided by next generation sequencing (NGS)-based ...
Immunophenotypic analysis indicated the lymphocytes were CD3+, CD8+ T expressing the alpha receptor and a leukointegrin, alpha d. Chemotherapy and splenectomy resulted in an initial reduction in the lymphocyte count.关键词: leukemia, T-lymphocytes, drug therapy, dogs, case studies, splenectomy ...
Diffuse large B-cell lymphoma (DLBCL) is the most common type of lymphoma in dogs. We evaluated Ki67 immunoexpression and mitotic index (MI) in dogs diagnosed with DLBCL and treated with a 19-wk CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone) protocol. Twenty-nine lymph node...
Diffuse large B-cell lymphoma (DLBCL) is the most common haematopoietic tumour in dogs and recognized as clinical model for its human counterpart. Recently, neutrophil-to-lymphocyte (NLR) and lymphocyte-to-monocyte (LMR) ratios have been shown to predict time-to-progression (TTP) and lymphoma-...
A large population study showed that intact female dogs had a significantly lower risk for developing lymphoma as compared with dogs that underwent gonadectomy (at a nonspecific age) or intact male dogs.38 This finding was consistent in studies of golden retrievers and vizslas, although castration ...
Humans and their pet dogs are close, so close that they both develop a type of cancer called diffuse large B-cell lymphoma. In humans it's the most common lymphoma subtype while in dogs, it's one of the most common cancers in veterinary oncology. ...
canine nodal diffuse large B‐cell lymphomaclinical signsprognosissubstagesurvivaltreatment responseIn humans B﹕ymptoms refer to systemic symptoms of lymphoma such as fever, weight loss, and night sweats and influence the prognosis of patients. In canine lymphoma, substage B is used to describe ...
Although these aggressive LGL lymphomas are still poorly known, they may be compared to three types of human lymphoma: aggressive NK cell lymphoma/leukemia, hepatosplenic T-cell lymphoma and enteropathy-type T-cell lymphoma.doi:10.1007/s00580-004-0531-5...
B-cell lymphomadogLymphomas are common in dogs and among them diffuse large B-cell lymphoma (DLBCL) represent ∼20%. The aim of this study was to evaluate and compare results of histopathological, immunohistochemical and fractal dimension (FD) analyses of canine DLBCL....
Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of lymphoma in dogs with a multicentric form. This study aimed to assemble 41 variants of the previously reported genes and to investigate these variants in canine DLBCL using the Agena MassARRAY platform. These variants were ...