Langerhans cell histiocytosis (LCH) is a bone marrow-derived immature myeloid dendritic cell proliferative disorder with diverse clinical manifestations commonly involves bone, skin, lymph node and lung. Oral involvement is uncommon. Intraoral lesions can be the first sign of either a localized LCH or...
Studies from patients with all stages of the disease, however, document clonal proliferation of immune processing cells (i.e., Langerhans cells), suggesting a malignant disease process. The most common ophthalmic manifestation of Langerhans cell histiocytosis is a solitary lesion of orbital bone, ...
Paediatric pulmonary Langerhans cell histiocytosis (pPLCH) is a rare condition and an important differential of cystic lung disease in children. 1 The aetiology of pPLCH is not completely understood. 1 It is classi ed as a neoplasm of haemopoietic mye-loid precursor cells, and the disease is ...
Clinical aspects of Langerhans cell histiocytosis. Hematol Oncol Clin North Am. 1998;12(2):247-258.Arico M, Egeler RM. Clinical aspects of Langerhans cell histiocytosis. HematolOncolClin North Am. 1998; 12:247-258.Arico M, Egeler RM. Clinical aspects of Langerhans cell histiocytosis. Hematol ...
Wohlschlaeger J, Ebert S, Sheu SY, Schmid KW, Totsch M. Immunocytochemical investigation of Langerin (CD207) is a valuable adjunct in the diagnosis of Langerhans cell histiocytosis of the thyroid. Pathol Res Pract. 2009;205:433-6.