(1)Leading strand is the DNA strand that synthesized continuously in the 5′ to 3′ direction as the parental duplex is unwound. It is primed one time during synthesis and uses the DNA strand 3’ to 5’ as template. 前导链是指随着亲本双螺旋的解开而按照5′ 3′方向连续合成的DNA子链...
百度试题 结果1 题目半不连续性: 领头链(leading strand) 随从链(lagging strand) 冈崎片段(Okazaki fragment)相关知识点: 试题来源: 解析 pol I,pol III 反馈 收藏
1990 . Sequential initiation of lagging and leading strand synthesis by two different polymerase complexes at the SV40 DNA replication origin . Nature 346 : 534 – 539 .Tsurimoto, T. , Melendy, T. and Stillman, B. , Sequential initiation of lagging and leading strand synthesis by two ...
Explain why DNA polymerase can continuously add fragments onto the leading strands 3'-5', but cannot do the same for the lagging strand. During transcription, on which strand will RNA polymerase be located? What is the role of DNA ligase in the elongation? What is the ...
coli is not the result of DNA repair processes. Furthermore, we show that the Okazaki fragments contain about equal amounts of leading- and lagging-strand sequences. These results are most consistent with the discontinuous DNA replication model as originally proposed by Okazaki et al. 展开 ...
题目 (翻译)The leading strand is synthesized continuously, while the lagging strand is synthesized in short stretches known as Okazakifragments. 相关知识点: 试题来源: 解析 正确答案:答:前导链是连续合成的,而后随链是以短的直线状的冈崎片段合成。 反馈 收藏 ...
Wagner J., Kamiya J., Fuchs R.P., Leading versus lagging strand mutagenesis induced by 8-dihydro-8-oxo-2'-deoxyguanosine in Escherichia coli, J. Mol. Biol. 265 (1997) 302-309.Wagner J, Kamiya H, Fuchs RPP (1997) Leading versus lagging strand mutagenesis induced by 7,8-dihydro-8-...
One of the strands, known as leading strand, is continuously created throughout DNA replication. The other, known as the lagging strand, is produced in pieces. This results in two semi-conservative DNA molecules, each with one old and another strand....
2007 . The eukaryotic leading and lagging strand DNA polymerases are loaded onto primer-ends via separate mechanisms but have comparable processivity in the ... O.,Chilkova,P.,... - 《Nucleic Acids Research》 被引量: 130发表: 2007年 The eukaryotic leading and lagging strand DNA polymerases ...
This finding supports the dimeric DNA polymerase model [(1980) J. Biol. Chem. 255, 4290–4303], which proposes that DNA polymerases δ and α act coordinately as leading and lagging strand enzymes, respectively, at the replication fork. 展开 ...