Because LDH is a nonspecific and general marker of tissue or cell damage, there are many circumstances that may prompt its use. You can ask your health care team about the purpose of LDH testing for your situation. Finding a Lactate Dehydrogenase (LDH) Test ...
Lactate dehydrogenase 5 (LDH-5) is one of the major isoenzymes catalyzing the biochemical process of pyruvate to lactate. The purpose of this study was to investigate the expression of serum LDH-5 and test whether this enzyme is regulated by tumor hypoxia and represents a prognostic marker in...
In a previous study, immuno-polymerase chain reaction (PCR) was shown to provide highly sensitive detection of Plasmodium falciparum lactate dehydrogenase (PfLDH) in monoclonal antibody (mAb) sandwich assays. Here, we show comparably high immunoassay sensitivity by inductively coupled plasma mass ...
at the same time, reduce the level of lactate dehydrogenase, and effectively inhibits thrombocytopenia and schistocyte hemolytic anemia, so as to achieve the purpose of the treatment of TTP, which has a good prospect of clinical use... LI Xiaoyi,X Dai 被引量: 0发表: 2019年 [Hemolytic Anem...
Moreover, it is likely for galactose-based lactagenesis to be secondarily affected at another site of iodoacetate susceptibility, 3-phosphoglyceral- dehyde dehydrogenase (EC 1.2.1.12). This glycolytic enzyme is pertinent to the catabolism of fructose as well as galactose. The iodoacetate suppression...
However, under anaerobic conditions, pyruvate dehydrogenase activity is inhibited, and lactate is the final product of glycolysis, becoming a substrate for gluconeogenesis in the Cori cycle. Therefore, lactate production is increased under hypoperfusion or stress conditions, causing an increase in ...
FAO and glycolysis remained highly expressed over the early immune response to the booster. Most intriguing, we also observed a profound decrease in lactate metabolism, i.e., downregulation of the lactate dehydrogenase encoding gene (LDHA) in the immune response induced by the booster compared to ...
18. Hussien R, Brooks GA Mitochondrial and plasma membrane lactate transporter and lactate dehydrogenase isoform expression in breast cancer cell lines. Physiol Genomics 43: 255–264. 19. Manning Fox JE, Meredith D, Halestrap AP (2000) Characterisation of human monocarboxylate t...
A. Intracellular localization of the particulate methane monooxygenase and methanol dehydrogenase in Methylomicrobium album BG8. Arch. Microbiol. 178, 59–64 (2002). 38. Bogorad, I. W. et al. Building carbon–carbon bonds using a biocatalytic methanol condensation cycle. Proceedings of the ...
This glycolytic phenotype is enabled by lactate dehydrogenase (LDH), which catalyzes the inter-conversion of pyruvate and lactate. The purpose of this study was to identify and characterize potent and selective inhibitors of LDHA. Methods High throughput screening and lead optimization were used to ...