Figure 5 shows a molecular model of the physical interactions between LacI and lac operators that play essential roles in the formation of the DNA topological barrier with 3 constrained (−) supercoils. As mentioned above, these constrained (−) supercoils are important for the lac operon....
The Operon Model and its Impact on Modern Molecular Biology Mitchell Lewis, in Journal of Molecular Biology, 2011 Abstract Few proteins have had such a strong impact on a field, as the lac repressor and λ repressor have had in Molecular Biology in bacteria. The genes required for lactose uti...
Interestingly, Sun and colleagues observed that the insertion of an ISaba1 into the adeS gene resulted in over-expression of adeABC operon hence the non-susceptibible phenotypes of clinical strains to tigecycline59. Additionally, AdeIJK appears to be regulated by AdeN, a TetR type of regulator...
The structure of vitellogenin provides a molecular model for the assembly and secretion of atherogenic lipoproteins 1999, Journal of Molecular Biology Show abstract Tuning the dials of synthetic biology 2013, Microbiology (United Kingdom) Combinatorial transcriptional control of the lactose operon of Escher...