(A) Images of a nanoprobe in solution taken using brightfield (left-hand panel) and fluorescence (middle panel). The right-hand panel is a diagram of a nanoprobe including dimensions of vertex cylinders and tip. (B) Schematic diagram of the flow cell showing an upper 'holding area' for ...
b, Topological diagram showing the h-type immunoglobu- lin-like fold of D1 and the s-type fold of D2. The -sheet at the D1–D2 interface (strands AЈ and G in D1 and a fragment of strand G in D2) is shown below D1. Loops L1–L6 are implicated in ligand binding by...