(A) Images of a nanoprobe in solution taken using brightfield (left-hand panel) and fluorescence (middle panel). The right-hand panel is a diagram of a nanoprobe including dimensions of vertex cylinders and tip. (B) Schematic diagram of the flow cell showing an upper 'holding area' for ...
The present invention relates to a method for the manufacture of labeled oligonucleotide conjugates comprising the reaction of (a) an oligonucleotide having a labile protecting grou