Phi, D.T. Tram, K. Eersels, P. Wagner, T.T. Lien, Development of an impedimetric sensor for the label-free detection of the amino acid sarcosine with molecularly imprinted polymer receptors, Sens. Actuators B:
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Innovative pro-regenerative treatment strategies for progressive multiple sclerosis (PMS), combining neuroprotection and immunomodulation, represent an unmet need. Neural precursor cells (NPCs) transplanted in animal models of multiple sclerosis have sho
Unlike conventional labels, the affinity label contains a reactive group which is able to form a covalent bond with a suitably oriented nucleophilic amino acid within the active site of the protein. The use of a radiolabeled form of an affinity reagent can therefore greatly expedite the ...
The representations of multi-view RNA features.AThe process of one hot encoding for RNA sequences. Through one-hot encoding, an RNA sequence of length n is converted into a blank matrix of size 4×n.BThe matrix of an amino acid sequence with size 20×n, which indicates the occurrence of...
We apply DIA-DOMs to capture subcellular localization changes in response to starvation and disruption of lysosomal pH in HeLa cells, which identifies a subset of Golgi proteins that cycle through endosomes. An imaging time- course reveals different cycling patterns and confirms the quantitative pre-...
and may lead to the loss of critical information. on the other hand, deep learning methods face challenges related to hardware performance and training time when handling complex sequences. they may suffer from the curse of dimensionality and overfitting problems. therefore, there is an urgent need...
Split Amino Acid Composition Pseudo Amino Acid Composition ML-KNN Rank-SVM SMOTE 1. Introduction Structure and location of a protein in a biological cell assists biologists in understanding the functions associated with it, especially in the context of the compartment of a cell where it resides. ...
aodmaipntaetdesbyovBeerrtnhseteointh, ewrhs einreeVxmprwesassioannt(ic1i)ptahteend it can be simplified to the Nernst equation: RT Vm = ln F cmed ccyto (2) awnhderneucmmeedraatnodr cbceytiondgeesxccrhibaengtheed external and internal concentrations of in the case of an anion being...
This technique is based on a change in polarizability of a molecule on the absorption of photons. In contrast, complementary infrared (IR) spectroscopy depends on a change in the dipole moment. Raman spectroscopy is an information-rich spec- troscopic method, like FT-IR, capable of detecting ...