The mobile phases were: A as 5 mM NH4OAc (≥99%, HiPerSolv CHROMANORM®, VWR) aqueous buffer, brought to pH = 5.6 with glacial acetic acid (≥99%, HiPerSolv CHROMANORM®, VWR) and B as pure acetonitrile (Roth, liquid chromatography–mass spectrometry (LC–MS) grade, purity ≥ ...
The phase calculation is done with the phase-locked loop (PLL) modulation with real-time phase shifts for the modeling waveforms, and each single waveform will be generated for three phases. For the generation model, disturbance patterns are applied with randomness among one or three phases, ...
Samples of the octanol (200 µL) and aqueous (200 µL) phases were taken and counted by γ-counter. LogD7.4 value was calculated by using the equation: LogD7.4 = log [(counts in octanol phase)/(counts in aqueous phase)]. All the experiments were performed in triplicates. Molecules...