this discipline has relied on the keen eyes of pathologists to make clinical judgments based on visual examinations of stained tissue sections under a microscope to classify diseases and determine their prognoses. The advent of whole slide imaging (WSI) scanners in the last decade has transformed ho...
Breast cancer is the most common type of cancer among women worldwide. The standard histopathology of breast tissue, the primary means of disease diagnosis, involves manual microscopic examination of stained tissue by a pathologist. Because this method relies on qualitative information, it can result...
We think this reflected the difference in permeability between the epithelium and endothelium of the cornea. Stratified corneal epithelium has tight junctions (TJs) at apical cell-cell contacts56 and they form a barrier that separates the eye from the outside. On the other hand, TJs of corneal...
Innovations in high-resolution optical imaging have allowed visualization of nanoscale biological structures and connections. However, super-resolution fluorescence techniques, including both optics-oriented and sample-expansion based, are limited in qua
The structures observed in these images were shown to match those observed using H&E stained sections. The morphological features were classified correctly as crypts, lumen, connective tissue, and musculature. In the second layer RF image (Fig. 2B third row), infiltrating inflammatory cells and ...