various methods have been proposed to deterministically make use of multiple-scattered waves1,2,3,4,5,6,7; however, the prevailing methods for biological imaging mainly involve compensating the sample-induced aberration in the context of adaptive optics (AO)8,9. Typical AO microscopy for deep-ti...
To fully leverage the diverse features of RNA, this paper proposes the construction of a multi-label deep learning model that integrates multiple RNA features to predict the interaction between RNA and RBP. The overall framework of our model is illustrated in Fig.1. The model comprises a feature...
We present a new label-free three-dimensional (3D) microscopy technique, termed transport of intensity diffraction tomography with non-interferometric synthetic aperture (TIDT-NSA). Without resorting to interferometric detection, TIDT-NSA retrieves the 3D refractive index (RI) distribution of biological...
Despite the development of several effective treatments that revolutionized the natural history of multiple sclerosis (MS), their advantages are mainly achieved for patients with relapsing-remitting MS (RRMS), while effective therapies for progressive MS (PMS) still represent an unmet need. In PMS, t...
fields (ELF-MF) caused an upregulation of the A2Areceptors expressed by blood cells5and cortical neurons6. Subsequently, they demonstrated that the application of ELF-MF has also a direct protective effect on hypoxic damage in neuron-like cells and an anti-inflammatory effect in microglial cells...
Therefore, viruses can generate detectable SERS signals when the surface molecules contact the nanostructured sensor [27]. Figure 3a shows the representative SERS spectra of SARS-CoV-2 RNA. In addition, it can be observed that the spectra show the typical SERS peaks associated with single-stranded...